Registration Dossier
Registration Dossier
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EC number: 244-870-1 | CAS number: 22252-43-3
Auto flammability
Administrative data
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25 January 2010 – 01 April 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: This study has been performed according to OECD and EC guidelines and according to GLP principles.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.16 (Relative Self-Ignition Temperature for Solids)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- EC Number:
- 244-870-1
- EC Name:
- (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- Cas Number:
- 22252-43-3
- Molecular formula:
- C8H10N2O3S
- IUPAC Name:
- 7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- Details on test material:
- - Name of test material (as cited in study report): 7-ADCA
- Molecular formula: C8H10N2O3S
- Molecular weight: 214.2
- Substance type: White powder
- Physical state: solid
- Analytical purity: 99.0%
- Impurities: -
- Isomers composition: -
- Purity test date: -
- Lot/batch No: D212013
- Expiration date of the lot/batch: 28 February 2011 (retest date)
- Stability under test conditions: Stable
- Storage condition of test material: In refrigerator (2-8°C) in the dark
- Other: Test substance handling: -
Constituent 1
Results and discussion
Relative self-ignition temperature (solids)
- Remarks on result:
- other: the test substance is considered ‘not self-ignitable’.
Any other information on results incl. tables
An exothermic effect of the test substance by self-heating was observed at an oven temperature of 195°C. During this effect the test substance reached a temperature of 245°C. According to the guideline, a test substance is self-ignitable when the sample temperature reaches 400°C by self-heating. Based on this, the test substance is considered ‘not self-ignitable’.
After the experiment, the test substance had turned into acharred residue and was still in the test cube. It indicated that the test substance had decomposed and/or reacted during the experiment.
Applicant's summary and conclusion
- Conclusions:
- The self-ignition temperature of 7-ADCA was determined using a temperature programmed laboratory oven, a stainless steel wire mesh cube, NiCr/NiAl thermocouples and a temperature recording device.
Based on the results obtained the test substance is considered ‘not self-ignitable’.
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