Registration Dossier
Registration Dossier
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EC number: 240-979-3 | CAS number: 16921-30-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
For dipotassium hexachloroplatinate, ecotoxicity data are read across from another platinum(IV) substance that also contains a chloro ligand, hexachloroplatinic acid. The 3-h EC50, EC10 and NOEC values without ATU (nitrification inhibitor) were determined to be 40.33 mg Pt L-1, 2.35 mg Pt L-1, and 1.26 mg Pt L-1, respectively. The 3-h EC50, EC10 and NOEC values with ATU were determined to be 32.49 mg Pt L-1, 3.21 mg Pt L-1, and 3.92 mg Pt L-1, respectively.
Key value for chemical safety assessment
Additional information
For dipotassium hexachloroplatinate, ecotoxicity data are read across from another platinum(IV) substance that also contains a chloro ligand, hexachloroplatinic acid.
An activated sludge respiration inhibition test was conducted with hexachloroplatinic acid following OECD guideline 209 and EU Method C.11 (Muckle 2015). Two test series were carried out, with and without the nitrification inhibitor N- allylthiourea (ATU) to discern between inhibition of nitrificators and inhibition of the total population. Based on a range-finding test where significant inhibition was observed, two additional tests were performed, where 5 concentrations ranging from 1 to 320 mg test item L-1 were tested with and without ATU, respectively. A positive control was used, and all validity criteria were met. Based on nominal concentrations, the 3-h EC50, EC10 and NOEC values without ATU were determined to be 103 mg test item L-1 (40.33 mg Pt L-1), 6.0 mg test item L-1 (2.35 mg Pt L-1), and 3.2 mg test item L-1 (1.26 mg Pt L-1), respectively. The 3-h EC50, EC10 and NOEC values with ATU were determined to be 83 mg test item L-1 (32.49 mg Pt L-1), 8.2 mg test item L-1 (3.21 mg Pt L-1), and 10 mg test item L-1 (3.92 mg Pt L-1), respectively.
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