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EC number: 227-101-4 | CAS number: 5655-61-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Skin irritation: Key study: Test method OECD 404.GLP study: Based on the read-across approach, laevo bornyl acetate was determined to be not irritating to the skin in accordance with CLP Regulation (EC) no. 1272/2008 and as irritating to the skin (Xi, R38) according to Directive 67/548/EEC.
Eye irritation: Key study: Test method OECD 405.GLP study: Based on the read-across approach, laevo bornyl acetate was determined to be not irritating to the eye.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Skin irritation: Key study: Read-across approach from experimental data on the analogue isobornyl acetate:
An in-vivo skin irritation test was performed on the analogue substance isobornyl acetate according to OECD 404. Three New Zealand White rabbits were exposed to 0.5 mL (unchanged) test sample under semi-occlusive conditions for 4 hours. After patch removal, the rabbits were observed at 30 -60 min, 24, 48 and 72 hours and 7 days. Two rabbits showed erythema score of 2 at mean 24 -72h time period, which was fully reversible by day 7. No edema was observed. Based on these results, the read-across approach was applied and laevo bornyl acetate was determined to be not irritating to the skin in accordance with CLP Regulation (EC) no. 1272/2008 and as irritating to the skin (Xi, R38) according to Directive 67/548/EEC.
Eye irritation: Key study: Read-across approach from experimental data on the analogue isobornyl acetate:
An in-vivo eye irritation test was performed on the analogue substance isobornyl acetate according to OECD Guideline 405. The right eye of three New Zealand White rabbits were exposure to 0.1 mL (unchanged) test sample. The other one was used as control. The effects were observed after 1, 24, 48 and 72 hours exposure. Two rabbits showed a chemosis score of 0.33 (mean 24 -72h) which was fully reversible after 48 hours of exposure. One rabbit showed a conjunctivae score of 0.66 (mean 24 -72h) which was fully reversible after 72 hours of exposure. Based on these results, the read-across approach was applied and laevo bornyl acetate was determined to be not irritating to the eye.
Justification for selection of skin irritation / corrosion endpoint:
Only one study available
Justification for selection of eye irritation endpoint:
Only one study available.
Justification for classification or non-classification
Based on the available information, laevo bornyl acetate is not classified for skin irritation and eye irritation in accordance with CLP Regulation (EC) no. 1272/2008. Besides, it is classified as irritating to skin (Xi, R38) according to Directive 67/548/EEC.
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