Registration Dossier
Registration Dossier
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EC number: 216-913-4 | CAS number: 1696-20-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to aquatic invertebrates.
Key value for chemical safety assessment
Additional information
The acute toxicity of 4 -acetylmorpholine (CAS 1696 -20 -4) was assessed via a read-across approach since no experimental data are available for this substance. Test data for Daphnia magna were taken from studies with other N-substituted morpholine structures. All studies are reliable with restrictions since no chemical verification of the test item concentrations was performed.
The following data were used:
- 4 -Methylmorpholine (CAS 109 -02 -4): 48 -h EC50 > 100 mg/L (BASF AG, 1991; Study No. 1/91/0270/50/1)
- 4 -Ethylmorpholine (CAS 100 -74 -3): 48 -h EC50 = 580 mg/L (BASF AG, 1989; Study No. 01/89/0733)
- 4 -Morpholinecarbaldehyde (CAS 4394 -85 -8): 48 -h EC50 > 500 mg/L (BASF AG, 1987; Study No. 1/1679/2/88)
Taking these values, it can be concluded that 4 -acteylmorpholine is acutely not harmful to aquatic invertebrates with a high probability.
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