Registration Dossier
Registration Dossier
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EC number: 273-054-8 | CAS number: 68937-17-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity to microorganisms: ASRI 3 hr EC50 >100mg/l (loading rate) (OECD 209) for read-across substance dichloro(methyl)(vinyl)silane
Key value for chemical safety assessment
Additional information
The submission substance is a multiconstituent substance with three major constituents: 1,2-dichloro-1,1,2,2-tetramethyldisilane, 1,1,2-trichloro-1,2,2-trimethyldisilane and 1,1,2,2-tetrachloro-1,2-dimethyldisilane. No reliable data are available for the toxicity to microorganisms of the submission substance. A toxicity to microorganisms study is, however, available for the related substance dichloro(methyl)(vinyl)silane. It is considered appropriate to read across the toxicity to microorganisms result for dichloro(methyl)(vinyl)silane because it is considered a close structural analogue of the submission substance. Both the submission substance and dichloro(methyl)(vinyl)silane will hydrolyse rapidly under conditions relevant to microbial toxicity assessment, to similar hydrolysis products, the dimethylsilanediol and methylsilanetriol for the submissions substance and methylvinylsilanediol for the read-across substance. The other hydrolysis product is hydrogen chloride. Effects of hydrogen chloride on microorganisms are limited to those that result from changes to pH in unbuffered media.
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