Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-599-9 | CAS number: 7647-15-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Key study: Test method according the Dutch Standard Organization (1980; NEN 6502). Test method equivalent or similar to OECD Guideline 211 (Daphnia magna Reproduction test). The 16d-NOEC and 16d-EC10 of sodium bromide in Daphnia magna were determined to be 2.8 and 43 mg/L, respectively.
Key study: Test method according to OECD (March 1995) Test Guideline Program: Draft Report of the Final Ring Test of the Daphnia magna Reproduction Test. The 21d-NOEC of sodium bromide in Daphnia magna was determined to be 7.5 mg/L.
Key study: Test method according to "Provisional Procedure: extended toxicology test with Daphnia magna (determination of NOEC for reproduction rate, mortality and the time of the first appearance of offspring; 21 d)" (Federal Environmental Agency). The 21d-NOEC value in Daphnia magna was determined to be 91 mg Br-/L (117 mg NaBr/L).
Key study: Test method according the Dutch Standardization Organization Guideline (1980; NEN 6502). Test method equivalent or similar to OECD Guideline 211 (Daphnia magna Reproduction test). The NOEC values of sodium bromide in Daphnia magna based on reproduction were determined to be 0.0078 g Br-/litre (0.01 g NaBr/L) for the P and F1 generation and 0.016 g Br-/litre (0.02 g NaBr/L) for the F2 generation.
Supporting study: No guideline followed. No analytical monitoring of the test substance was made. The 40d-NOEC value of sodium bromide in Lymnaea stagnalis was determined to be 10 mg/L.
Supporting study: No guideline followed. No analytical monitoring of the test substance was made. The 21d-NOEC value of sodium bromide in Daphnia magna was determined to be 10 mg/L.
Supporting study: No guideline followed. No analytical monitoring of the test substance was made. The 21d-NOEC value of sodium bromide in the freshwater specie Hydra oligactis was determined to be 1000 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2.8 mg/L
Additional information
Key study: A 16 day toxicity test in Daphnia magna was performed with the test substance sodium bromide, in accordance with the Dutch Standard Organization (1980; NEN 6502) and following a method equivalent or similar to OECD Guideline 211. 20 -25 daphnids were exposed to different concentrations of sodium bromide increased with a factor of 1.8. At the end of the exposure period, the length from the top of the head to the end of the tail of each daphnid was measured to determine the NOEC and EC10 values based on growth changes. The 16d-NOEC and 16d-EC10 were determined to be 2.8 and 43 mg/L, respectively.
Key study: A long-term toxicity test onDaphnia magnawas performed with the test substance sodium bromide in accordance with the OECD (March 1995) Test Guideline Program: Draft Report of the Final Ring Test of the Daphnia magna Reproduction Test. Daphnids were exposed to nominal concentrations of 3, 7.5, 19, 47 and 117 mg/liter over an exposure period of 21 days in a semi-static system. A comparison was made of the results obtained after first-brood release and after 21 days of exposure. Sodium bromide significantly affected D. magna reproduction both at the release of the first brood and at the end of the test. Furthermore, NOECs and LOECs determined in both periods were identical (7.5 mg/L and 19.0 mg/L, respectively). EC50 based on reproduction was determined to be 20.8 mg/L. Growth was not affected by sodium bromide either after release of the first brood or after 21 days of exposure.
Key study: A 21 d Daphnia magna reproduction test was performed with the test item sodium bromide in accordance with the provisional procedure proposed by the Federal Environmental Agency: extended toxicology test with Daphnia magna (determination of NOEC for reproduction rate, mortality and the time of the first appearance of offspring; 21 d). Daphnia magna Straus organisms were exposed to test substance concentrations ranging from 3 to 11,444 mg/L. The concentrations of the test substance in the test preparations were chemically quantified. Evaluation parameters for fixing the NOEC were the mortality of the parent animals, the reproduction rate and the appearance of the first offspring during the test period. The NOEC based on reproduction was determined to be 91 mg Br-/L (117 mg NaBr/L).
Key study: A Daphnia reproduction test was performed with the substance sodium bromide in accordance with the Dutch Standardization Organization Guideline (1980; NEN 6502) and following a method equivalent or similar to OECD Guideline 211. 25 daphnids per vessel were exposed to the test substance for 23 days. The test organisms were observed for mortality and reproductive effects. A NOEC value of 0.0078 g Bromide ion/litre (0.01 g NaBr/L) for the P and F1 generations and a NOEC value of 0.016 g Br-/L (0.02 g NaBr/L) for the F2 generation were derived from the reproductive performance. Besides, it was found a concentration-related decrease in the total number of eggs produced per female per batch in the brood-chamber, as well as a concentration related decrease in the viability of these eggs. The EC50 based on the reproductive effects was stated to be 0.023 g Br-/L (0.0296 g NaBr/L) for P, F1 and F2 generation. The LC50 was determined to be 6.1 g Br-/L (7.85 g NaBr/L).
Supporting study: A long-term toxicity test of sodium bromide was carried out on the freshwater mollusc Lymnaea stagnalis. The organisms were exposed to different concentrations of the test substance over a period of 40 days in a semi-static system. The LC0 (No lethal concentration) was determined to be 3200 mg/L. The NOEC value based on reproduction was stated to be 10 mg/L.
Supporting study: A long-term toxicity test in Daphnia magna was performed with the test substance sodium bromide. 25 daphnids (1 day old) per replicate were exposed to different concentrations of the test item for 21 days under semi-static conditions. The daphnids were observed for mortality and reproductive effects. The LC0 (No lethal concentration) was determined to be 3200 mg/L and the NOEC value, based on reproduction, was reported to be 10 mg/L.
Supporting study: A long-term toxicity test with sodium bromide was carried out on the freshwater specie Hydra oligactis. The organisms were exposed to different concentrations of the test substance over a period of 21 days in a semi-static system. The effect parameter measured was the specific growth rate. The NOEC based on growth rate was stated to be 1000 mg/L, after a 21 day exposure period.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.