Registration Dossier
Registration Dossier
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EC number: 909-044-3 | CAS number: -
Endpoint summary
Administrative data
Description of key information
There is no aquatic toxicity data available for phosphonic ester residue. However, there are short toxicity studies on algae [cited as Directive 92/69/EEC, C.3; in most parts equivalent to the OECD TG 201] and invertebrates [cited as Directive 92/69/EEC, C.2; in most parts equivalent to the OECD TG 202] with one of the main components of the substance, dimethyl phosphonate (DMP, CAS 868-85-9) available. Within those studies, a rapid and complete hydrolysis of DMP to monomethyl phosphonate (CAS 13590-71-1, MMP) was observed. MMP, the main component of phosphonic ester residue, slowly hydrolyses to the third main component phosphonic acid (CAS 13598-36-2, PA). In addition, OECD 201 and OECD 202 studies with PA are available.
Taking those information together, it is plausible to derive the EC50 for phosphonic ester residue from the available studies on DMP and PA. As worst case approach the lowest value is taken:
OECD 201 (DMP), GLP, Desmodesmus subspicatus, 72 h-EC50 = 100 mg/L (nominal)
OECD 202 (DMP), GLP, Daphnia magna, 48h-EC50 = 24.8 mg/L (nominal)
Additional information
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