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Diss Factsheets
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EC number: 201-837-6 | CAS number: 88-51-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Non-GLP guideline study without analytical test item concentration verification
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 986
- Report date:
- 1986
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: EG-1 published by EPA, 1982
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-amino-4-chloro-5-methyl benzoic sulfonic acid sodium salt
- IUPAC Name:
- 2-amino-4-chloro-5-methyl benzoic sulfonic acid sodium salt
- Details on test material:
- - Name of test material (as cited in study report): Chlor-p-Toluidinsaeure Na Salz
- Analytical purity: no data
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: great waterflea
- Source: Originally obtained from the Institut National de Recherche Chimique Appliquee, France, since 1978 inhouse culture at BASF
- Age at study initiation (mean and range, SD): 6 - 24 h
- Method of breeding: Cultured in water with a total hardness of 2.5 ± 0.5 mM CaCO3, a Ca:Mg ratio of 4:1 and an oxygen content of > 2mg/L at a temperature of appr. 20 °C. 16:8 hours light:dark, light intensity appr. 5 µEinstein/(m2*s); wave length range from 400 - 750 nm
- Food type: brewers yeast and green algae suspension
- Frequency: brewers yeast at water exchange and green algae suspension daily, not on saturdays, sundays and bank holidays
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 3 mM (at test start)
- Test temperature:
- 20 °C
- pH:
- 7.86 - 8.02
- Dissolved oxygen:
- 8.02 - 9.0 mg/L
- Nominal and measured concentrations:
- nominal: control, 62.5, 125, 250, 500 mg/L
- Details on test conditions:
- TEST SYSTEM
- Test vessel: centrifuge tubes with flat bottom
- Material, size, headspace, fill volume: 10 mL fill volume
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Dechlorinated charcoal filtered tap water, the acid constnat was adjusted to 4.3 using H2SO4, the total hardness was adjusted using distilled water
- Ca/Mg ratio: 4:1
- Conductivity: 650 µSiemens/cm (at test start)
OTHER TEST CONDITIONS
- Photoperiod: darkness
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : mobility
TEST CONCENTRATIONS
- Spacing factor for test concentrations: 2
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 500 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 500 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.