p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]benzenesulphonamide

Auto flammability

Administrative data

Endpoint:

auto-flammability

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2002

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: The study was conducted by a well experienced research laboratory and in accordance with several internationally acknowledged guidelines.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2002

Report date:

2002

Materials and methods

Principles of method if other than guideline:

Equipment:
An oven with a quartz intern wall ((Ø = 36,5 mm; H = 220 mm), which can go up to the rnaximum ternperature of 600°C, and a dispersion device
constitute the equipment.
The oven is controlled by a thermocouple placed in the quartz tube wall with a temperature regulator.
The powder dispersion device is constituted by a container in which he sample is placed, a pressure reducer, a small device with a manometer and
the fluid to disperse (air or oxygen-nitrogen mixture) and one electrovalve.
The reducer regulates the optimum deposit pressurisation value and when the experiment takes place the electrovalve opening is controlled to
obtained, with the gassy fluid flow, the powder transport and consequent powder dispersion in the oven (the powder placed in the container)

Procedure:
Approximately 100mg of the powder to examine are placed in the container, if possible with a particle size less than 75mm; when the oven
temperature is near the desired value, the powder dispersion in the oven, putting on the electrovalve, is done.
The electrovalve opening allow the small deposit of gassy fluid, previously stored at the pressure value (0, 1 - 2 bar) appropriate for the powder
typology, to flow.
The dispersion production can be observed by a mirror placed inside the reactor, if there is no phenomenon visible the test will be repeated at
superior temperature, from 10°C to 10°C. Otherwise if the powder cloud ignition is manifested, the test will be repeated at inferior temperature, from 10°C to 10°C, until reach the minimum ignition temperature.
More tests are done, varying the powder quantity used, as weil as the deposit fluid pressure, with the target of determine the minimum temperature at which the ignition of the cloud takes place.
lt is assumed as ignition temperature in cloud of the sample to exam, the minimum oven temperature value which result is positive and minor than
10°C.

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]benzenesulphonamide

EC Number:

251-529-0

EC Name:

p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]benzenesulphonamide

Cas Number:

33456-68-7

Molecular formula:

C20H22N2O5S

IUPAC Name:

4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzene-1-sulfonamide

Results and discussion

Auto-ignition temperature (liquids / gases)

Auto-ignition temperature:

460 °C

Remarks on result:

other: Dust cloud ignition temperatur

Relative self-ignition temperature (solids)

Relative self-ignition temperature:

460 °C

Remarks on result:

other: Dust cloud ignition temperatur

Any other information on results incl. tables

The ignition temperature in cloud of the examined sample, that has been obtained dispersing the powder directly in the assay equipment, is represented in the following table.

Sample	Tcloud (°C)
Fase X (ARDF-26)	460

Applicant's summary and conclusion

Conclusions:

The dust cloud ignition temperature is moderately high, because this, furthermore to avoid the dust cloud formation, you must avoid to hand it near to surfaces at this temperature