Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 940-422-0 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Glucamide 818 read across justification 'Aquatic ecotoxicity'
For read across the following C chain homologeuous Glucamides are used, being already registered under REACH:
| Public name | REACH name | EC No. | Carbon chain | |||||
| Glucamide 810 | 1-deoxy-1-[methyl(C8-10-(even)-alkanoyl)amino]-D-glucitol, REACH Registration No. 01-2120028964-50-0000 |
940-284-2 | C8-10 | |||||
| Glucamide 1214 | A 3:1 mixture of: 1-deoxy-1-[methyl-(1-oxododecyl)amino]-D-glucitol; 1-deoxy-1-[methyl-(1-oxotetradecyl)amino]-D-glucitol, REACH Registration No. 01-0000015674-66-0001 |
407-290-1 | C12-14 | |||||
| Glucamide 1618 | A mixture of: 1-deoxy-1-[methyl-(1-oxohexadecyl)amino]-D-glucitol; 1-deoxy-1-[methyl-(1-oxooctadecyl)amino]-D-glucitol, REACH Registration No. 01-0000015858-56-0000 |
411-130-6 | C16-18 | |||||
Based on the typical composition of Glucamide 818 65.7% a.i. is related to C12 & C14 homologues (Glucamide 1214) and 13.8% a.i. to C8 & 10 (Glucamide 810). C16 to C18 & C18-1 account for 17.3% a.i. only. This means that the aquatic ecotoxicity values for Glucamide 818 should be higher than the ones from Glucamide 1214 but lower than the values from Glucamide 810.
For read across the lower aquatic ecotoxicity values will be taken, means the values from Glucamide 1214 (worst case).
In the table below an overview on the acute & chronic aquatic ecotoxicity of the the registration substance Glucamide 818 is given together with the data from Glucamide 1214. Comparing the data from Glucamide 818 and Glucamide 1214 shows that GA 1214 can be used for read across for the missung acute and chronic fish data of Glucamide 818 as the other acute and chronic data of both substance are in the same order of magnitude. Read across for the fish data avoids verterbrate testing and contributes to animal welfare.
Table Summary of the available acute & chronic aquatic ecotoxicity data of Glucamide 818 and Glucamide 1214
| Type | Species | Guideline | Endpoint | GA 818 (a.i.) | GA 1214 (a.i.) | |
| Acute fish | Danio rerio | OECD 203 | LC50 (96h) | 7.5 mg/L (RA GA1214) |
7.5 mg/L | |
| Acute daphnia | Daphnia magna | OECD 202 | EC50 (48h) | 5.9 mg/L | 18 mg/L | |
| Algae | S. capricornutum | OECD 201 | ErC50 (96h) | 49 mg/L | 30 mg/L | |
| Microorganisms | Sewage sludge | OECD 209 | NOEC (3h) respiration inhibition | 8.1 mg/L | 8.9 mg/L | |
| Chronic fish | Danio rerio | OECD 210 | NOEC (35d) mortality | 4.8 mg/L (RA GA1214) |
4.8 mg/L | |
| Chronic daphnia | Daphnia magna | OECD 211 | NOEC (21d) mortality | 3.2 mg/L | 4.3 mg/L | |
| Algae | S. capricornutum | OECD 201 | ErC10 (96h) | 7.2 mg/L | 6.4 mg/L |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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