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EC number: 231-679-3 | CAS number: 7681-82-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data is from peer reviewed journal
- Justification for type of information:
- Data is from peer reviewed journal
- Qualifier:
- according to guideline
- Guideline:
- other: Refer below principle
- Principles of method if other than guideline:
- Aim of this study was to determine the effect of test chemical on the mortality of daphnia magna. Test conducted for 48 hrs under the static system.
- GLP compliance:
- no
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- SPECIES (NAME) : Daphnia magna (Water Flea)
AGE : <=24 h - Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Hardness:
- 54.4 mg/L CaCO3
- Test temperature:
- 20 degC
- pH:
- 8.0
- Dissolved oxygen:
- 10.1 mg/L
- Salinity:
- Not Reported
- Details on test conditions:
- ALKALINITY : 47 mg/L CaCO3
CONDUCTIVITY : 256 umhos/cm
TEST LOCATION : LAB
APPLICATION FREQ. : 1 X - Reference substance (positive control):
- not specified
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.17 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: Other details not known
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The lethal concentration (LC50) value of test chemical in aquatic invertebrate (Daphnia magna) on mortality effect is observed to be 0.17 mg/L.
- Executive summary:
Aim of this study was to determine the effect of test chemical on the mortality of daphnia magna. Test conducted for 48 hrs under the static system. <=24 hours old water flea used as a test organism. The lethal concentration (LC50) value of test chemical in aquatic invertebrate (Daphnia magna) on mortality effect is found to be 0.17 mg/L.Thus considering the CLP Criteria for aquatic classification of the substance ,it can be assumed that test chemical could exhibit toxicity to aquatic invertebrate (Daphnia magna) in the aquatic acute 1 classification category.
Reference
Description of key information
Aim of this study was to determine the effect of test chemical on the mortality of daphnia magna. Test conducted for 48 hrs under the static system. <=24 hours old water flea used as a test organism. The lethal concentration (LC50) value of test chemical in aquatic invertebrate (Daphnia magna) on mortality effect is found to be 0.17 mg/L.Thus considering the CLP Criteria for aquatic classification of the substance ,it can be assumed that test chemical could exhibit toxicity to aquatic invertebrate (Daphnia magna) in the aquatic acute 1 classification category.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.17 mg/L
Additional information
Various short term studies available for the test chemical were reviewed to determine the toxic nature of test chemical on the mobility of aquatic invertebrates. The studies are as mentioned below:
The first key study was for the determination of the effect of test chemical on the mortality of daphnia magna. Test conducted for 48 hrs under the static system. <=24 hours old water flea used as a test organism. The lethal concentration (LC50) value of test chemical in aquatic invertebrate (Daphnia magna) on mortality effect is found to be 0.17 mg/L.Thus considering the CLP Criteria for aquatic classification of the substance ,it can be assumed that test chemical could exhibit toxicity to aquatic invertebrate (Daphnia magna) in the aquatic acute 1 classification category.
First study was supported by the second study from peer reviewed journal. Aim of this study was to determine the effect of test chemical on the mortality of daphnia magna. Test conducted for 48 hrs under the static system. <=24 h old daphnia were used for the toxicity measurement. Test performed under the static system. The lethal concentration (LC50) value of test chemical in aquatic invertebrate (Daphnia magna) on mortality effect was observed to be 0.23 mg/L. Thus considering the CLP Criteria for aquatic classification of the substance, it can be assumed that test chemical could exhibit toxicity to aquatic invertebrates and classified in the aquatic acute 1 classification category.
Similar short term toxicity of test chemical was studied on the growth of freshwater water flea daphnia magna. Test conducted under the static system for 48 hrs. <=24 hrs old daphnia magna were used as a test organism. Based on the mortality of daphnia magna by the chemical exposure for 48 hrs, the LC50 value was determine to be at 0.43 mg/l and 0.78 mg/l also with the slight changes occurs in the temperature, pH and hardness of water. Thus considering the CLP Criteria for aquatic classification of the substance, it can be consider that the test chemical could exhibit toxicity to aquatic invertebrate (Daphnia magna) and classified in the aquatic acute 1 classification category.
Similarly aim of this study was to determine the effect of test chemical on the mobility and Floatability of test daphnia magna by providing the exposure period of 24 hrs. Test conducted under the static system. 24 h old daphnia magna were used in the study. After the exposure of test chemical with daphnia magna for 24 hrs, no effect were observed on the mobility and floating behavior at 1 mg/l. Effects i.e EC50 was observed at the concentration 13 mg/l. Thus based on the EC50 value, it can be concluded that the chemical is toxic and can be consider to be classified as aquatic chronic 3 category as per the CLP classification criteria.
Thus based on the all above studies, chemical consider to be toxic to the aquatic invertebrates and classified in aquatic acute category 1 as per the CLP classification criteria.
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