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EC number: 235-762-5 | CAS number: 12672-27-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
The ecotoxicity databases on the effects of soluble cobalt and aluminium compounds to aquatic, soil- and sediment-dwelling organisms are extensive. It should be noted that the environmental fate pathways and ecotoxicity effects assessments for cobalt metal and cobalt compounds as well as for aluminium metal and aluminium compounds is based on the observation that adverse effects to aquatic, soil- and sediment-dwelling organisms are a consequence of exposure to the bioavailable ion, released by the parent compound. The result of this assumption is that the ecotoxicological behaviour will be similar for all soluble cobalt and aluminium substances used in the ecotoxicity tests.
As cobalt aluminium oxide has shown to be highly insoluble with regard to the results of the transformation/dissolution test protocol (pH 6, 28 d), it can be assumed that under environmental conditions in aqueous media, the components of the substance will be present in a bioavailable form only in minor amounts, if at all. Within this dossier all available data from cobalt and aluminium substances are pooled and used for the derivation of ecotoxicological and environmental fate endpoints, based on the cobalt ion and aluminium ion. For cobalt, only data from soluble substances were available and for aluminium, both soluble and insoluble substance data were available. All data were pooled and considered as a worst-case assumption for the environment. However, it should be noted that this represents an unrealistic worst-case scenario, as under environmental conditions the concentration of soluble Co2+ and Al3+ ions released is negligible.
Conclusion on classification
Classification related key information
Water solubility: Transformation/dissolution test (28 d, OECD 29)
7 d: 0.72 µg Co/L (1 mg/L loading), < 1 µg Al/L (1 mg/L loading)
28 d: 0.6 µg Co/L (0.1 mg/L loading), 3.6 µg Co/L (1 mg/L loading), < 1 µg Al/L (0.1 and 1 mg/L loading)
Biodegradation in water: not applicable (inorganic substance)
Aquatic acute toxicity:
to fish: 96 h, LC50 (Oncorhynchus mykiss): 1.406 mg Co/L, RA
to algae: 5 d, ErC50 (Ditylum brightwellii): 0.3 mg Co/L, RA
to crustacea: 48 h, EC50 (Daphnia magna): 1.49 mg Co/L, RA
to aquatic plants: 96 h, EC50 (Spirodela polyrhiza): 0.14 mg Co/L, RA
Aquatic chronic toxicity:
to fish: 16 d, NOEC (Brachydanio rerio): 0.06 mg Co/L, RA
to algae: 21 d, NOErC (Chlorella vulgaris): 0.6 mg Co/L, RA
to crustacea: 21 d, NOEC (Daphnia magna): 0.03 mg Co/L, RA
Classification justification according to CLP
Based on the data above, there is no evidence of rapid environmental transformation of cobalt aluminium oxide.
The concentration of Co at 1 mg/L loading rate for the 7d value of the T/D test is lower than the acute Environmental Reference Value (0.14 mg Co/L). Furthermore the concentration of Co at 1 mg/L loading rate is lower than the chronic ERV (0.03 mg Co/L).
Therefore, following the “Guidance on the application of the CLP criteria, IV. Metals and inorganic metal compounds (ECHA, 2012)" according to Regulation (EC) 1272/2008 (CLP) with regard to the results of the transformation/dissolution test, cobalt aluminium oxide does not need to be classified and labelled as environmental hazard according to the Regulation (EC) No.1272/2008 (CLP) and the Regulation (EU) No. 286/2011 (2ndATP).
M-factor
for acute aquatic toxicity: -
M-factor
for chronic aquatic toxicity: -
Classification justification according to DSD
Based on the data above, there is no evidence of rapid environmental transformation of cobalt aluminium oxide. However, for aquatic plants there is an EC50 of 0.14 mg/L available which was chosen as acute Environmental Reference Value. Valid chronic toxicity data are available - the NOEC of 0.03 mg Co/L for Daphnia was chosen as chronic Environmental Reference Value.
Therefore, cobalt aluminium oxide needs to be classified and labelled as environmental hazard N; R50/53 according to Directive 67/548/EEC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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