Eucalyptus radiata australiana, ext.

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

April, 19-20, 2022

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

The study has been conducted according to internationally recognised guideline, under GLP. No deviation from guideline are reported. The substance is adequately characterized. Therefore full validation applies.

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

1995

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

GLP-BESCHEININGUNG Statement of GLP Compliance (inspected on 28-29 April 2021, signed on 21 June 2021)

Type of method:

differential scanning calorimetry

Boiling pt.:

>= 183.01 - <= 185.55 °C

Atm. press.:

998.2 mBar

Remarks on result:

other: range of max of peaks

Boiling pt.:

>= 158.71 - <= 173.22 °C

Atm. press.:

998.2 mBar

Remarks on result:

other: onset

Boiling pt.:

>= 117.26 - <= 224.87 °C

Atm. press.:

998.2 mBar

Remarks on result:

other: range (min- max) of endothermic envents

Calibration

The measurement of Indium after calibration mets the validity criteria. 

Main Test

Three measurement were performed as the deviation of the onset between the first and second determination was too high (> 0.5 K) therefore a third measurement was performed.

Table 1 - Results

Beginning of boiling process	in °C (event mark)	in K
1 Determination	131.41	404.56
2 Determination	117.26	390.41
3 Determination	121.45	394.60
Min	117.26	390.41
Max	131.41	404.56
Ending of boiling process	in °C (event mark)	in K
1 Determination	224.87	498.02
2 Determination	216.55	489.70
3 Determination	218.58	491.73
Min	216.55	489.70
Max	224.87	498.02
Onset	in °C	in K
1 Determination	173.22	446.37
2 Determination	158.71	431.86
3 Determination	166.65	439.80
Min	158.71	431.86
Max	173.22	446.37
Peak max	in °C	in K
1 Determination	185.55	458.70
2 Determination	184.67	457.82
3 Determination	183.01	456.16
Min	183.01	456.16
Max	185.55	458.70

The ambient atmospheric pressure was recorded to be 998.2 mbar in all measurements.

Table 2 - Observation

	Mass test item	Mass crucible (before measurement):	Mass crucible (after measurement):	Observations
First Measurement	1.61 mg	46.62 mg	45.12 mg	After the test the crucible was visually unchanged (weight loss: 1.50 mg, i.e. : 93.2%)
Second Measurement	1.58 mg	46.57 mg	45.10 mg	After the test the crucible was visually unchanged (weight loss: 1.47 mg, i.e. : 93.0%)
Third Measurement	1.58 mg	46.74 mg	45.27 mg	After the test the crucible was visually unchanged (weight loss: 1.47 mg, i.e. : 93.0%)

As the test item is a UVCB substance a boiling range can be expected. Therefore, a boiling range is stated for the test item EUCALYPTUS RADIATA OIL:

- The endothermic event ranged from 117.26 °C to 224.87 °C (390.41 K to 498.02 K)

- The peak maximum ranged from 183.01 °C to 185.55°C (456.16 K to 458.70 K).

- The Onset was determined in a range from 158.71 °C to 173.22 °C (431.86 K to 446.37 K)

 

 

 

Conclusions:

The range of boiling occurred from 117.26 °C to 224.87 °C (390.41 K to 498.02 K) at 998.2 mBar.
The onset of boiling was observed in the range from 158.71 °C to 173.22 °C (431.86 K to 446.37 K) at 998.2 mBar.

Executive summary:

The boiling point of the test substance was determined under GLP according to OECD 103 / EU A2 guideline, using the DSC method.

Three main runs were performed, under inert atmosphere.

As the test item is a UVCB substance a boiling range can be expected. Therefore, a boiling range was stated at 998.2 mBar for the test item:

- The endothermic event ranged from 117.26 °C to 224.87 °C (390.41 K to 498.02 K)

- The peak maximum ranged from 183.01 °C to 185.55°C (456.16 K to 458.70 K).

- The Onset was determined in a range from 158.71 °C to 173.22 °C (431.86 K to 446.37 K)

Description of key information

The range of boiling occurred from 117.26 °C to 224.87 °C (390.41 K to 498.02 K) at 998.2 mBar.
The onset of boiling was observed in the range from 158.71 °C to 173.22 °C (431.86 K to 446.37 K) at 998.2 mBar.

Additional information

A fully reliable experimental study, conducted according to a recognised EC method and under GLP, is available. It is considered as a key study.