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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 473-080-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Emergency measure - Inhalation: Move promptly to fresh air. If appropriate rinse mouth and
nose thoroughly with water. If breathing stops administer
artificial respiration. Administer oxygen if breathing is
difficult. Obtain medical advice immediately.
Emergency measure - Eyes: Wash out with water or saline solution for at least 15
minutes, including under eyelids. If persistant irritation
is present seek medical advice.
Emergency measure - Skin: Remove contaminated clothing and wash affected skin with
soap and water. If adverse reaction occurs or persists seek
medical advice.
Emergency measure - Ingestion: Rinse mouth with water. Do not induce vomiting. Seek
medical attention immediately.
Fire-fighting measures
Recommended extinguishing agent: Dry powder, foam, carbon dioxide
Product arising from burning: None known, however incomplete combustion may produce
harmful oxides of carbon and nitrogen
Product determined by test: N
Protective equipment: Wear self contained breathing apparatus and protective suit.
Accidental release measures
Emergency measures in case of spillage: Wear suitable protective clothing to minimise contact with
skin or eyes and respiratory protection to prevent
inhalation. Contain the spillage, sweep up, place in bag and
hold for waste diposal. Avoid raising dust and wash spill
site after material pick up is complete. Avoid discharge to
drains/surface water.
Handling and storage
Handling: (S)-AMI.HCl is handled in two operations only- sampling and
dispensing to IBCs. Both operations are conducted inside
downflow booths designed for the specific operation.
Sampling: The sampling booth is a stand-alone unit located
in the warehouse, consisting of two separate "rooms" - an
inner sampling area, and an airlock through which personnel
ans materials for sampling must pass. Air is extracted by a
fan from the inner sampling area, and recircilated through
a pre-filter and HEPA filter back into the sampling area
(90%) and airlock (10%). Local gauges are fitted in the
sampling area, allowing the operator to monitor the booth
operation condition:
- sampling area pre-filter and HEPA differential pressures
(Dp)
- airlock pre-filter and HEPA differential pressures (Dp)
- Dp between sampling area and airlock
- Dp between airlock and warehouse
- airflow through sampling area
Dispensing: The dispensing booth is a downflow booth located
in a dedicated dispensing room. This room is separarted
from the main production facility by two airlocks - one for
personnel entry and one for materials entry. The booth is
open to the dispensing room on one side, but airflow pattern
is designed to provide containment within a defined safe
working area. There is a 10% bleed of filtered exhaust air
back to the dispensing room, and 10% make-up of fresh air
supply from the room to the booth. Local gauges are fitted
at the booth entrance, allowing the operator to monitor the
booth operating condition:
- coarse dust, fine dust and HEPA filter differential
pressures
- booth airflow
Appropriate personal protective equipment to be worn when
handling (S)-AMI.HCl:
Respiratory protection - dust mask or full-face respirator
(EN 136)
Hand protection - disposable nitrile gloves (EN 374-2-374-3)
Eye protection - goggles (EN 166)
Skin protection - disposable, impermeable outer garments
including boot covers and hat (EN 340/EN 365)
Storage: Keep tightly closed in a cool, dry and well ventilated
place. Keep away from heat and sources of ignition. Store
in original container.
Packaging of the substance and or preparation: Substance is packaged in 50kg fibre drums (net fill weight
30kg of substance per drum) within double polyethlyene bag
with tamperproof lids.
Transport information
Shippingopen allclose all
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
Shippingopen allclose all
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
Shippingopen allclose all
Special provisions / remarks
- Remarks:
- Transport code: UN3077
Transport: Transport in sealed, unbreakable containers secured against
falling or other shock.
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Stability and reactivity
Danger other than fire: None known.
Chemical reaction with water: None known.
Dust explosion: Dust cloud ignition at 440 degrees C.
No ignition for 5mm dust layer, which melts over approx. 200
degrees C.
Miniumum ignition energy of dust/air mixture was 1-10J.
Dust explosion determined by test: Y
Disposal considerations
Industry - Possibility of recovery/recycling: Not applicable
Industry - Possibility of neutralisation: Neutralisation is not necessary
Industry - Possibility of destruction: controlled discharge: Not recommended
Industry - Possibility of destruction - incineration: Recommended
Industry - Possibility of destruction - water purification: Not recommended
Industry - Possibility of destruction - other: Not recommended
Public at large - Possibility of recovery/recycling: Not applicable: no sale to consumers will occur
Public at large - Possibility of neutralisation: Not applicable: no sale to consumers will occur
Public at large - Possibility of destruction: controlled discharge: Not applicable: no sale to consumers will occur
Public at large - Possibility of destruction - incineration: Not applicable: no sale to consumers will occur
Public at large - Possibility of destruction - water purification: Not applicable: no sale to consumers will occur
Public at large - Possibility of destruction - others: Not applicable: no sale to consumers will occur
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.