Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 459-330-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Surface tension
Administrative data
- Endpoint:
- surface tension
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 03/AUG/04 - 26/OCT/04
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 115 (Surface Tension of Aqueous Solutions)
- Deviations:
- yes
- Remarks:
- Temperature of test solution for test 2 was out of range. Because the measurements for the test solution were started without a previous equilibration period, the temperature of the test solution was not yet in equilibration with the water bath used.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.5 (Surface Tension)
- Deviations:
- yes
- Remarks:
- Temperature of test solution of test 2 was out of range. Because the measurements for the test solution were started without a previous equilibration period, the temperature of the test solution was not yet in equilibration with the water bath used.
- GLP compliance:
- yes
- Type of method:
- ring method
Test material
- Reference substance name:
- 1,1,2,2-tetrafluoroethyl-2,2,2-trifluoroethyl ether
- EC Number:
- 609-858-6
- Cas Number:
- 406-78-0
- Molecular formula:
- C4H3F7O
- IUPAC Name:
- 1,1,2,2-tetrafluoroethyl-2,2,2-trifluoroethyl ether
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- Asahiklin AE-3000, molecular weight 200.07
CAS 406-78-0
Clear colourless liquid
Batch 50407070
Purity: 99.985%
The test substance was stored in a refrigerator in the dark under stable conditions
The test substance expiry date was the 07 July 2005
Results and discussion
Surface tensionopen allclose all
- Key result
- Surface tension:
- 71 mN/m
- Temp.:
- 20 °C
- Conc.:
- 560 mg/L
- Key result
- Surface tension:
- 72 mN/m
- Temp.:
- 21.5 °C
- Conc.:
- 560 mg/L
Any other information on results incl. tables
In order to calculate the surface tension, the value from the apparatus was multiplied by the calibration factor. Determination of the calibration factor was as follows:
Φb= σo/ σg
Where:
σo = surface temperature of water at the test temperature cited in the literature
σg = measured surface tension of the water at the test temperature
Surface tension of water at 20°C (Test 1)
Measurement |
Time expired (minutes) |
Surface tension (mN/m) |
|
Measured |
Mean σg |
||
1 |
30 |
71.9 |
71.9 |
2 |
31 |
71.8 |
|
3 |
32 |
71.8 |
|
4 |
33 |
71.8 |
|
5 |
34 |
72.0 |
σo= 72.59 mN/m (at 20.0°C)
Φb= σo/σg=1.010
Surface tension of water at 20°C (Test 1)
Measurement |
Time expired (minutes) |
Surface tension (mN/m) |
|
Measured |
Mean σg |
||
1 |
20 |
70.8 |
71.4 |
2 |
21 |
71.4 |
|
3 |
22 |
71.3 |
|
4 |
23 |
71.4 |
|
5 |
24 |
71.4 |
|
6 |
25 |
71.5 |
σo= 72.59 mN/m (at 20.0°C)
Φb= σo/σg=1.017
However, this only yielded approx. results and required additional correction using a table compiled on the basis of the Harkins-Jordan correction (see table below):
Experimental value (mN/m) |
Corrected value (water calibration) (mN/m) |
Experimental value (mN/m) |
Corrected value (water calibration) (mN/m) |
20 |
18.1 |
50 |
48.6 |
22 |
20.1 |
52 |
50.7 |
24 |
22.1 |
54 |
52.8 |
26 |
24.1 |
56 |
54.9 |
28 |
26.1 |
58 |
57.0 |
30 |
28.1 |
60 |
59.1 |
32 |
30.1 |
62 |
61.3 |
34 |
32.1 |
64 |
63.4 |
36 |
34.1 |
66 |
65.5 |
38 |
36.1 |
68 |
67.7 |
40 |
38.2 |
70 |
69.9 |
42 |
40.3 |
72 |
72.0 |
44 |
42.3 |
74 |
- |
46 |
44.4 |
76 |
- |
48 |
46.5 |
78 |
- |
The tables below show the individual measurements and the corrected surface tensions for the test solutions prepared in tests 1 and 2. The temperatures of the test solutions were 20.0°C and 12.0 -21.5°C respectively. GC analysis showed that the test solution of test 2 contained approx. 560mg/L of test substance after the last measurement. This meant that the aqueous test solution still contained a large amount of test substance during the measurements.
Surface tension of an aqueous solution (Test 1):
Measurement |
Time expired (minutes) |
Surface tension (mN/m) |
|||
Measured |
Mean not corrected |
Mean corrected for calibration |
Mean corrected using Harkibs and Jordan |
||
1 |
48 |
70.8 |
70.9 |
71.6
|
71.2 |
2 |
49 |
70.7 |
|||
3 |
50 |
71.0 |
|||
4 |
51 |
71.1 |
|||
5 |
52 |
71.0 |
Surface tension of an aqueous solution (Test 2):
Measurement |
Time expired (minutes) |
Surface tension (mN/m) |
|||
Measured |
Mean not corrected |
Mean corrected for calibration |
Mean corrected using Harkibs and Jordan |
||
1 |
1 |
71.1 |
71.1 |
72.3 |
72.3 |
2 |
2 |
71.1 |
|||
3 |
3 |
71.0 |
|||
4 |
4 |
71.1 |
|||
5 |
5 |
71.1 |
Applicant's summary and conclusion
- Conclusions:
- In conclusion, the surface tension test result of test 1 was 71mN/m (20.0°C) and the surface tension test result of test 2 was 72mN/m (21.0-21.5°C).
Therefore, according to the criteria as outlined in the EEC guideline, 1,1,2,2-tetrafluoroethyl-2,2,2-trifluoroethyl ether is not surface active (substances showing a surface tension lower than 60mN/m under the conditions of this method should be regarded as surface active materials). - Executive summary:
An experiment was carried out to determine the surface tension of 1,1,2,2-tetrafluoroethyl-2,2,2-trifluoroethyl ether. In order to do this, the ring method was used and measurements were repeated until a constant surface tension value was reached. Two tests were carried out; the first following usual protocol and the second taking utmost care to minimise evaporation of the test substance, which would affect the values obtained. In order to calculate the surface tension, the value read on the apparatus was multiplied by the calibration factor Φb. However, this yielded only an approximate value, which was then corrected for using a table compiled on the basis of Harkins-Jordan corrected. Based on this correction, the surface tension of test 1 was determined to be 71mN/m (20.0°C) and the surface tension test result of test 2 was determined to be 72mN/m (21.0-21.5°C). Therefore, according to the criteria as outlined in the EEC guideline, 1,1,2,2-tetrafluoroethyl-2,2,2-trifluoroethyl ether is not surface active
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.