Benzoyl chloride, 3-[[[2,3-bis(acetyloxy)propyl]amino]carbonyl]-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2001

Report date:

2001

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

GLP compliance:

no

Type of method:

effusion method: Knudsen cell

Test material

Test material information

Constituent 1

Reference substance name:

rac-3-(2,3-Diacetoxypropylcarbamoyl)-2,4,6-triiodo-5-methoxyacetylaminobenzoyl chloride

EC Number:

604-759-4

Cas Number:

150928-21-5

Molecular formula:

C18 H18 Cl I3 N2 O8

IUPAC Name:

rac-3-(2,3-Diacetoxypropylcarbamoyl)-2,4,6-triiodo-5-methoxyacetylaminobenzoyl chloride

Results and discussion

Vapour pressure

Temp.:

25 °C

Vapour pressure:

< 0.001 Pa

Applicant's summary and conclusion

Conclusions:

Vapour pressure: < 0.001 Pa at 25 °C

Executive summary:

The vapor pressure of ZK 91445 was determined using a screening method based on the detection of the evaporation rate from a Knudsen cell of a vapor pressure balance at 25°C. Since simplified experimental conditions are also acceptable within the scope of this project, ZK 91445 was mixed with four other compounds. From all five test substances low or very low vapor pressures, based on the study director’s experience, were expected. For this reason the experiments consisted in the measurement of the evaporation rate of the mixture from a Knudsen cell a 25 °C. Since the evaporation rate of the mixture was below the value derived from the lower limit of the vapor pressure range recommended for the use of a vapor pressure balance (10E-03 Pa, EC Testing Guideline A.4) it can be assumed that the vapor pressure of the mixture is lower than 10E-03 Pa. Considering this fact, the vapor pressure of the single compounds in the mixture has also to be lower than 10E-03 Pa.