Registration Dossier
Registration Dossier
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EC number: 411-950-4 | CAS number: 96562-58-2 DHPPME; MAK-ME; MEHPOPS; R-MAQ-ME
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Under the conditions of this study, the 48 h EC50 value was 90.9 mg/L with 95 % CL of 67.2 to 122.9 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 90.9 mg/L
Additional information
The acute toxicity of the test material to Daphnia magna was investigated in accordance with the standardised guideline EU Method C.2 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
Acute toxicity of the test material to Daphnia magna was assessed in an acute immobilisation test over an exposure period of 48 hours in a static test system. Daphnids were exposed to the test material at 0.78, 1.56, 3.13, 6.25, 12.5, 25.0, 50.0 and 100 mg/L. The amount of test material in the test solutions was determined through UV/Vis spectroscopy.
Swimming ability of the test animals was observed visually after 0, 3, 6, 24 and 48 h. Animals which were considered to be immobile were unable to swim within 15 seconds after gentle agitation.
At 100 mg/L, 12 daphnids were considered to be immobile at 48 h. At the 50 and 25 mg/L exposure levels, 2 and 1 daphnids were considered to be immobile, respectively.
The validity criteria were fulfilled.
Under the conditions of this study, the 48 h EC50 value was 90.9 mg/L with 95 % CL of 67.2 to 122.9 mg/L.
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