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EC number: 406-850-2 | CAS number: 133855-98-8 BAS 480 F
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
The 28 -d NOEC (initial measured, emergence and development) was determined to be > = 674.5 µg/kg sediment dw in an OECD 218 GLP-guideline test with Chironomus riparius (Backfisch, 2008)
The 21 -d NOEC (nominal, analytically verified, emergence) was determined to be > 0.0625 mg/L in an OECD 218 GLP guideline test with Chironomus riparius, water-spiked (BASF AG, 1995)
Key value for chemical safety assessment
- EC10, LC10 or NOEC for freshwater sediment:
- 674.5 µg/kg sediment dw
Additional information
The sediment organism Chironomus sp. was exposed to Epoxiconazole and the number of emerged animals as well as signs of intoxication of the animals was recorded during a test period of 28 days. The test was set up according to OECD guideline 218 with artificial sediment. Analytical verification of test item concentrations was conducted in each concentration. Recoveries in the sediment were in a range between 90.5% - 106.6% of the nominal concentrations at test initiation. The following initial concentrations were measured: 113.1, 183.4, 269.2, 402.5 and 674.5 µg/kg dry sediment. At test termination the detected concentrations ranged from 85.4% - 98.6%. The biological results are based on initial measured concentrations. A 28 -d NOEC of >= 674.5 µg/kg sediment was determined (initial measured, emergence and development; Backfish, 2008).
In addition, a GLP study conducted according to OECD 218 (water-spiked) is also available for epoxiconazole. In a 21-day static, spiked water toxicity laboratory study, Chironomus riparius were exposed to nominal concentrations of 0.00625 and 0.0625 mg/L. The endpoint derived in this study was the 21-days NOEC ≥ 0.0625 mg/L. Since no effects up to the highest test concentrations were observed, no ECx calculations are possible. The test concentrations were analytically measured in both studies.
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