Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-183-4 | CAS number: 1310-65-2
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1976
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- other:
- Title:
- ECHA disseminated Dossier of Lithium hydroxide (CAS 1310-65-2)
- Year:
- 2 022
- Bibliographic source:
- ECHA disseminated Dossier of Lithium hydroxide (CAS 1310-65-2), query date 2022-03-09
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Lithium hydroxide, monohydrate
- EC Number:
- 603-454-3
- Cas Number:
- 1310-66-3
- Molecular formula:
- LiOH*H2O
- IUPAC Name:
- Lithium hydroxide, monohydrate
Constituent 1
Test animals
- Species:
- rabbit
- Sex:
- male/female
Administration / exposure
- Type of coverage:
- occlusive
- Vehicle:
- water
- Duration of exposure:
- 24 h
- Doses:
- 200, 3000 mg/kg bw
Results and discussion
Effect levelsopen allclose all
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 200 - <= 3 000 mg/kg bw
- Based on:
- test mat.
- Remarks:
- LiOH monohydrate
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 114 - <= 1 714 mg/kg bw
- Remarks on result:
- other: calculated for LiOH anhydrous
- Mortality:
- No mortality occurred at the 200 mg/ kg bw dose group. 4/4 animals died at 3000 mg/kg bw dose group.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
