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Diss Factsheets
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EC number: 209-090-8 | CAS number: 555-31-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
1. HYPOTHESIS FOR THE ANALOGUE APPROACH
[Describe why the read-across can be performed (e.g. common functional group(s), common precursor(s)/breakdown product(s) or common mechanism(s) of action]
Aluminium triisopropanolate reacts instantaneously with water to form iso-propanol and Al3+ species.Therefore an experimental study cannot be performed. Instead the log Pow was calculated, although this model calculation may be of low relevance due to the rapid hydrolysis. The partition coefficient was calculated to be 0.93. The log Pow of its hydrolysis product isopropanol is 0.05 and this would be the relevant value. The resulting Al3+ species are inorganic and do not need to be considered for the partition coefficient.
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
CORRESPONDING STANDARD INFORMATION REQUIRED
SOURCE
Isopropanol; CAS 67-63-0
Analytical purity: pure
Information on the physicochemical properties
State of matter: liquid
Water solubility (g/L) at 20˚C: completely miscible at 20 °C
Partition coefficient n-octanol/water: estimated to be 0.05
Vapour pressure: 60.53 hPa at 25 °C
Molecular weight: 60.095 g/mol
TARGET
Aluminium triisopropanolate; CAS 555-31-7
Information on the physicochemical properties
State of matter: solid
Water solubility (g/L) at 20˚C: The substance reacts instantaneously with water to form iso-propanol and
Al3+ species
Partition coefficient n-octanol/water: estimated to be 0.93
Vapour pressure: no data available
Molecular weight: 204.25 g/mol
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Exploring QSAR - Hydrophobic, Electronic, and Steric Constants
- Author:
- Hansch, C., Leo, A., D. Hoekman
- Year:
- 1 995
- Bibliographic source:
- Washington, DC: American Chemical Society., 1995., p. cited in Hazardous Substances Data Base (PubChem Compound Identifier CID3776), a database of the National Library of Medicine's TOXNET system http:pubchem.ncbi.nlm.nih.gov/), online query 2022-01-26
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Data from handbook or collection of data no data about the method was available.
- GLP compliance:
- no
- Type of method:
- other: QSAR
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Propan-2-ol
- EC Number:
- 200-661-7
- EC Name:
- Propan-2-ol
- Cas Number:
- 67-63-0
- Molecular formula:
- C3H8O
- IUPAC Name:
- propan-2-ol
- Details on test material:
- - Name of test material (as cited): Propan-2-ol
- Analytical purity: 99.95 ± 0.01 %
Constituent 1
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 0.05
- Temp.:
- 25 °C
- Remarks on result:
- other: Value from peer reviewed database. No data available for temperature and pH value. Usually the log Pow is calculated at 25 °C.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.