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Diss Factsheets
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EC number: 616-995-5 | CAS number: 8018-01-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Short-term toxicity to soil macroorganisms except arthropods
In accordance with REACH Annex XI a short-term study does not need to be conducted because an appropriate long-term toxicity study on terrestrial organisms is available. Additional data on short-term toxicity is scientifically not necessary; therefore, this endpoint was waived.
Long-term toxicity to soil macroorganisms except arthropods
In a GLP-compliant study according to ISO Guideline 11268-2 with Eisenia fetida the 28-day LC50 was determined to be > 161 mg a.i./kg. The 28 day no-observed-effect-concentration (NOEC) for mortality and growth was 161 mg a.i./kg. The 56-day NOEC for reproduction was 20 mg a.i./kg based on reduced number of offspring per adult earthworm. The NOECcorr considered for the Risk Assessement is 10 mg a.s./kg dw soil.
Short-term toxicity to terrestrial arthropods
In accordance with REACH Annex XI a short-term study does not need to be conducted because an appropriate long-term toxicity study on terrestrial arthropods is available. Additional data on short-term toxicity is scientifically not necessary. Therefore, this endpoint was waived.
Short-term toxicity to terrestrial arthropods
The long-term toxicity to terrestrial arthropods was assessed in a study with Hypoaspis aculeifer similar to OECD TG 225. The 21-day LR50 was determined to be > 4.3 mg a.s./kg dry soil (equivalent to LR50 > 3200 g a.s./ha). Based on reproduction, the ER50 was > 4.3 mg a.s./kg soil dw (equivalent to ER50 > 3200 g a.s./ha). The endpoint for consideration in the risk assessment is NOEC mortality = 2.1 mg/kg soil dw.
Short-term toxicity to terrestrial plants
In accordance with REACH Annex XI a short-term study does not need to be conducted because an appropriate long-term toxicity study on terrestrial organisms is available. Additional data on short-term toxicity is scientifically not necessary. Therefore, this endpoint was waived.
Long-term toxicity to terrestrial plants
In a study according to OECD TG 227 the 21-day ER50 and NOEC for the test item was determined to be > 1836 g product/ha and 1836 g product/ha (nominal), which corresponds to >1408 g a.s./ha and 1408 g a.s./ha, respectively. This value was re-calculated to be 1.872 mg/kg soil dw. The NOER (all effects) was assessed to be 1836 g product/ha (corresponding to 1408 g a.s./ha and 1.872 mg/kg soil dw, respectively).
Toxicity to sooil microorganisms
In a study according to the OECD Test Guideline No. 216 with Mancozeb the 56-day NOEC on nitrogen transformation in soil was determined to be 10 mg/kg soil dw.
Toxicity to birds
In an one-generation study following the principles of EPA Guideline OPPTS 850.2300 the18-week NOEC was determined to be 18.6 mg a.s./kg bw/d.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.