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EC number: 482-200-1 | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Version / remarks:
- Adopted: 17th July 1992
- Qualifier:
- according to guideline
- Guideline:
- other: Testing Guidelines for studies of Chemicals
- Version / remarks:
- Notification No. 2018-12, issued by the National Institute of Enviromental Research, Korea on April 9, 2018
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Lot No. 180705
Purity: 99.08%
Appearance: White crystal
Molecular Weight: 693.57 g/mol
Molecular Formula: C36H30N3O6P3
Storage condition: Room temperature - Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- Inoculum used in this study was collected from 12 sites in Korea including 5 rivers (Gangjeong, Mulgeum, Gurye, Gapcheon, Paldang), 4 domestic sewage treatment plants (Dalseo, Gumi, Busan, Asan) and 3 industial wastewater treatment plants (Dalseo, Yeosu, Tancheon). Fresh samples collected from these sites were incubated for over one month and the activated sludge greater than 10^7 cells/mL was used in this test.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Parameter followed for biodegradation estimation:
- O2 consumption
- Reference substance:
- aniline
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 14 d
- Remarks on result:
- not readily biodegradable based on QSAR/QSPR prediction
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
- Remarks on result:
- not readily biodegradable based on QSAR/QSPR prediction
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The test substance could not be concluded as a readily degradable substance by micoorganisms in the aquatic enviroment because the percentage biodegradation of the test substance by BOD measurement was less than pass level for ready biodegradability (60%) specified in the OECD guideline.
- Executive summary:
Microbial degradation of Phenoxycycloposphazene was performed for 28 days following Testign Guidelines for Studies of Chemicals. Section 4.3, "Biodegradation Study (Ready Biodegradability): Modified MITI(I)"(Notification No. 2018 -12, issued by the National Institute of Environmental Research, Korea on April 9, 2018) and OECD Guidelines for Testing of Chemicals, 301C, "Ready Biodegradability-MITI(I)"(Adopted:17th July 1992).
The results of microbial degradation of Phenoxycycloposphazene are as follows:
(1) The percentage biodegradations of the reference compound, aniline, observed by BOD measurement were 70.0% after 7 days and 78.0% after 14 days. The test was valid that the results were within the acceptable range specified in th OECD guideline.
(2) The pertage biodegradation of the test substance, Phenoxycycloposphazene observed by BOD meansurement was calculated to be negative value ~ 0.0% for 28 days. Therefore, these results indicated that the test substance is not biodegradable in aqueous condition. The percentage biodegradation based on the residual amount of test substance by HPLC analysis was calculated to be 5.9%.
As a result, the test substance could not be concluded as a readily degradable substance by micoorganisms in the aquatic enviroment because the percentage biodegradation of the test substance by BOD measurement was less than pass level for ready biodegradability (60%) specified in the OECD guideline.
Reference
Description of key information
The percentage biodegradations of the test substance, Phenoxycycloposphazene observed by BOD measurement was calculated to be negative value 0.0% for 28 days. Therefore , these results indicate that the test substance is not biodegradable in aqueous condition.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
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