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EC number: 427-440-1 | CAS number: 24487-91-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2 December 1996
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted to GLP in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
Test material
- Reference substance name:
- -
- EC Number:
- 427-440-1
- EC Name:
- -
- Cas Number:
- 24487-91-0
- Molecular formula:
- C9H9ClO2
- IUPAC Name:
- 2-Methyl-3-methoxy benzoyl chloride
- Test material form:
- other: solid mass
- Details on test material:
- MMBC
Physical state: light brown solid
Constituent 1
Results and discussion
Vapour pressure
- Temp.:
- 25 °C
- Vapour pressure:
- 0.34 Pa
Any other information on results incl. tables
Vapour Pressure Measurement by Mass Difference
RUN 1
A plot of Log(Vapour Pressure / Pa) vs Reciprocal Temperature (K / T) for Run 1 gives the following statistical data using an unweighted least squares treatment:
Slope: -3623.325
Intercept: 11.751
Standard deviation in Slope: 376.294
above as % of Slope: 10.385
Standard deviation in Intercept: 1.261
above as % of Intercept: 10.730
The results obtained indicate the following Vapour Pressure relationship:
Log Vp(Pa) = (-3623.325 (± 376.294) / Temp (K)) + 11.751 (± 1.261)
This yields a calculated vapour pressure of Vp(298.15 K) = 3.964^-01 Pa (-1.124^-03 / + 1.127^-03)
RUN 2
Slope: -2870.947
Intercept: 9.079
Standard deviation in Slope: 67.042
above as % of Slope: 2.335
Standard deviation in Intercept: 0.223
above as % of Intercept: 2.451
The results obtained indicate the following Vapour Pressure relationship:
Log Vp(Pa) = (-2870.947 (± 67.042) / Temp (K)) + 9.079 (± 0.23)
This yields a calculated vapour pressure of Vp(298.15 K) = 2.818^-01 Pa (-1.500^-03 / + 1.508^-03)
RUN 3
Slope: -913.376
Intercept: 1.742
Standard deviation in Slope: 77.903
above as % of Slope: 8.529
Standard deviation in Intercept: 0.260
above as % of Intercept: 14.927
The results obtained indicate the following Vapour Pressure relationship:
Log Vp(Pa) = (-913.376 (± 77.903) / Temp (K)) + 1.742 (± 0.260)
This yields a calculated vapour pressure of Vp(298.15 K) = 4.771^-02 Pa (-1.375E-04 / + 1.379^-04)
DISCUSSION
The solid sample was maintained below 39.5 °C during experiments and the small amount remaining showed no signs of melting or decomposition. The sample did not condense onto the balance pan. For stability reasons the temperature range was restricted.
The initial measured mass difference of Run 1 was 162.5 ug at 15.1 °C (equivalent to about 2.1 x 10^-1 Pa) with values rising to a maximum of 993 µg (equivalent to around 1.3 Pa) at 37.25 °C. Run 1 measured mass difference data gave a vapour pressure relationship yielding the rounded value Vp (25 °C) = 3.96 ± 0.01 x 10^-1 Pa as the interpolated vapour pressure.
After pumping during recooling, the initial measured mass difference of Run 2 was 128 µg at 18.35 °C (equivalent to about 1.7 x 10^-1 Pa) with values rising ultimately to 547 µg at 38.35 °C (equivalent to around 7.1 x 10^-1 Pa). Run 2 measured mass difference data gave a vapour pressure relationship yielding the rounded value Vp (25 °C) = 2.82 ± 0.015 x 10^-1 Pa as the interpolated vapour pressure.
After pumping during recooling, the initial measured mass difference of Run 3 was 27.2 µg at 15.5 °C (equivalent to about 3.5 x 10^-2 Pa) with values rising to 50 µg at 39.5 °C. Run 3 measured mass difference data gave a vapour pressure relationship yielding the rounded value Vp (25 °C) = 4.77 ± 0.015 x 10^-2 Pa as the interpolated vapour pressure.
Taking into account the small amount remaining on final inspection after Run 3 the rounded mean of the Run 1 and 2 values, Vp (25 °C) = 3.40 x 10^-1 Pa is the recommended vapour pressure.
Applicant's summary and conclusion
- Conclusions:
- The vapour pressure of the test substance at 25 °C was determined to be 3.40 x 10^-1 Pa.
- Executive summary:
The vapour pressure of the test substance was determined in accordance with standardised guideline EU Method A.4 using the vapour pressure balance. Under the conditions of the test, the vapour pressure of the test substance at 25 °C was determined to be 3.40 x 10^-1 Pa.
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