Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 472-110-0 | CAS number: 71868-15-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- Version / remarks:
- Annex V, C.7
- GLP compliance:
- yes
- Preliminary study:
- The result of preliminary test showed that less than 50% of ESACURE 2006 has been hydrolysed in 2.5 hours at 50°C, and less than 10% has been hydrolysed after 5 days, for the three pH values (4.0, 7.0 and 9.0) tested. No full test was performed in according with the methodology. Finally ESACURE 2006 can be considered with an abiotic degradation hydrolysis lower than 10% after 5 days at 50°C for pH 4.0, pH 7.0 and pH 9.0.
- Transformation products:
- no
- Key result
- pH:
- 4
- Temp.:
- 50 °C
- DT50:
- 5 d
- Remarks on result:
- hydrolytically stable based on preliminary test
- Key result
- pH:
- 7
- Temp.:
- 50 °C
- DT50:
- 5 d
- Remarks on result:
- hydrolytically stable based on preliminary test
- Key result
- pH:
- 9
- Temp.:
- 50 °C
- DT50:
- 5 d
- Remarks on result:
- hydrolytically stable based on preliminary test
- Details on results:
- At all pH, there was less than 10% hydrolysis of the test substance
- Conclusions:
- Based on the results of the study, the test substance is considered to be hydrolytically stable.
- Executive summary:
A study was conducted to evaluate the rate of hydrolysis of the test substance as a function of pH according to EU Method C.7, in compliance with GLP. The hydrolytic stability was investigated in buffer solutions of pH 4, 7 and 9 in a water bath at 50ºC for 5 days. Samples were taken at t0 and at regular intervals afterwards to determine half-life (t½). According to the guideline, if t½ is less than 2.4 h, or if less than 10% of the test substance is hydrolysed in 5 d, no further tests need to be performed at that pH. Under the conditions of the study, after 5 days at 50°C, less than 10% decrease in test substance concentration was measured at all three pH values. Therefore, the test substance was concluded to be hydrolytically stable with a half-life equal to or greater than one year at pH 4, 7 and 9 at ambient temperature (ChemService, 2007).
Reference
Description of key information
Based on the results of the study, the test substance is considered to be hydrolytically stable.
Key value for chemical safety assessment
Additional information
A study was conducted to evaluate the rate of hydrolysis of the test substance as a function of pH according to EU Method C.7, in compliance with GLP. The hydrolytic stability was investigated in buffer solutions of pH 4, 7 and 9 in a water bath at 50ºC for 5 days. Samples were taken at t0 and at regular intervals afterwards to determine half-life (t½). According to the guideline, if t½ is less than 2.4 h, or if less than 10% of the test substance is hydrolysed in 5 d, no further tests need to be performed at that pH. Under the conditions of the study, after 5 days at 50°C, less than 10% decrease in test substance concentration was measured at all three pH values. Therefore, the test substance was concluded to be hydrolytically stable with a half-life equal to or greater than one year at pH 4, 7 and 9 at ambient temperature (ChemService, 2007).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.