Copper bis(dimethyldithiocarbamate)

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

25-26 April 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)

GLP compliance:

yes

Type of method:

HPLC method

Partition coefficient type:

octanol-water

Analytical method:

high-performance liquid chromatography

Key result

Type:

log Pow

Partition coefficient:

ca. 4.55 - ca. 4.55

Temp.:

20 °C

pH:

ca. 8 - ca. 8

Results on test material - copper dimethyldithiocarbamate

Sample	Detector	Retention time (mins)		Peak Area (%)		k		Log k		Log Pow
		Run 1	Run 2	Run 1	Run 2	Run 1	Run 2	Run 1	Run 2	Run 1	Run 2
Peak 1	UV	4.080	4.080	99.33	99.29	0.38	0.38	-0.42	-0.42	1.23	1.23
	RI	-	-	-	-	-	-	-	-	-	-
Peak 2	UV	5.067	5.053	0.34	0.38	0.72	0.71	-0.14	-0.15	6.29	6.26
	RI	-	-	-	-	-	-	-	-	-	-
Peak 3	UV	10.387	10.327	0.16	0.14	2.52	2.50	0.4	0.4	6.29	6.26
	RI	-	-	-	-	-	-	-	-	-	-
Peak 4	UV	13.660	13.647	0.17	0.19	3.64	3.63	0.56	0.56	7.27	7.26
	RI	-	-	-	-	-	-	-	-	-	-

Conclusions:

Using DCM to solution copper dimethyldithiocarbamate due to its insolubility in methanol the Log Pow was determined to be 4.54 and 4.57 by UV detection (No response by RI). The average of these two runs gave a Percentage adjusted Pow of 4.55

Executive summary:

The Percentage adjusted Pow of Copper dimthyl dithiocarbamate was found to be 4.55 by UV detection in an octanol/water system.

Key value for chemical safety assessment

Log Kow (Log Pow):

4.55