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EC number: 308-662-5 | CAS number: 98171-53-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In an OECD 202 with Daphnia magna the test item reveal after 48 h exposure a toxicity (related to loading rates ) of EL 50 = 26.08 mg/l and an EL10 of 8.08 mg/l.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 26.6 mg/L
Additional information
Immobilisation of Daphnia magna exposed to the test item, Efka FA 4600 (solvent free), was investigated during a 48-hour semi-static test. The definitive test was performed with the following filtrates of the test item loading rates of 200, 100, 50, 25, 12.5 and 6.25 mg/L plus the control. The test was performed in glass beakers of 150 mL capacity. Each replicate contained 100 mL of either the filtrate of the test item loading rate or the control. Four replicates were used for each treatment, each with fiveDaphnia magna.
The test item is an UVCB substance soluble in water. Since precipitations of the test item were observed in the first preliminary test, the water accommodation fractions (WAFs) approach was used.
The test item loading rates were prepared by mixing the proper amounts of the test item withthe ISO test water.The test item loading rates and the control were filtered through a conditioned (pre-filtering a small volume of either the test loading rate or control to saturate the filter) nitrocellulose membrane filter(0.22 µm,Millipore).After 24 h of exposure, the filtrates of the test item loading rates and the filtrate of the control were renewed.
No immobilisation ofDaphnia magnawas observed during the period of exposure in the filtrate of the control. Immobilisation in the filtrates of the test item loading rates of 6.25, 12.5, 25, 50, 100 and 200 mg/L were 5, 20, 55, 70, 90 and 100%, respectively. Inthe filtrate of the control and in filtrate of the test item loading rate of 6.25 mg/L no abnormal behaviour ofDaphnia magnawas observed. In the filtrates of the higher test item loading rates slow movement ofDaphnia magnawas observed. In each filtrate of the test item loading ratesDaphnia magnawas covered with particles of the test item. In the filtrate of the test item loading rate of 200 mg/L precipitation of the test item was observed.
Since the test item is an UVCB, treatments analyses were performed usingtotal organic carbon (TOC) assum parameter.The total organic carbon analyses were performed in samples of each filtrate of a loading rate and the control at exposure initiation, at renewal and at exposure termination.
In the control, the analysed total organic carbon concentration remained below the LoQ value (<1.0 mg C/L)at exposure initiation, at renewal (fresh and old samples) and at exposure termination.
In the filtrate of the test item loading rates of 6.25, 12.5, 25, 50, 100, 200 mg/L, the analysed total organic carbon concentration was 1.5, 3.6, 6.3, 12.4, 21.0, 42.0 mg C/L, at exposure initiation, 1.5, 3.9, 6.7, 11.0, 19.3, 40.7 mg C/L at renewal in fresh samples, 1.6, 3.7, 6.4, 11.8, 20.2, 42.1 mg C/L in old samples and 1.5, 3.6, 6.7, 9.6, 18.2, 38.3 mg C/L at exposure termination, respectively.
Results:
The endpoint valuesdetermined based on the nominal test item loading ratesare given below:
ELR50(48h) is 26.68 mg/L (95% confidence interval 20.02 – 35.14 mg/L).
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