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Diss Factsheets
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EC number: 233-482-8 | CAS number: 10193-99-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Based on read across from PETMP, PETMA is assumed to be harmful if swallowed (LD50 = 1500 mg/kg bw) and non-toxic if inhaled (no mortality at highest attainable concentration).
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- see category report attached as "full study report"
- Reason / purpose for cross-reference:
- read-across source
- Principles of method if other than guideline:
- read across from PETMP using OECD QSAR Toolbox 4.2 using Structural Similarity as descriptor
- Species:
- rat
- Route of administration:
- oral: gavage
- Key result
- Dose descriptor:
- LD50
- Effect level:
- 1 500 mg/kg bw
- Based on:
- act. ingr.
- Remarks:
- read across from PETMP
- Interpretation of results:
- Category 4 based on GHS criteria
- Conclusions:
- Based on read across from PETMP, PETMA is classified as Acute Tox 4 - H302
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 1 500 mg/kg bw
- Quality of whole database:
- read across from valid study
Acute toxicity: via inhalation route
Link to relevant study records
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- see category report attached as "full study report"
- Reason / purpose for cross-reference:
- read-across source
- Principles of method if other than guideline:
- read across from PETMP using OECD QSAR Toolbox 4.2 using Structural Similarity as descriptor
- Species:
- rat
- Route of administration:
- inhalation: aerosol
- Key result
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- > 3 363 mg/m³ air (analytical)
- Based on:
- other: read across
- Exp. duration:
- 4 h
- Remarks on result:
- not determinable due to absence of adverse toxic effects
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Based on read across from PETMP, the 4-h LC50 of PETMA is considered >3.36 mg/L which was the highest attainable concentration of PETMP. Since both substances haver similar visosities, they are assumed to have a similar behaviour when atomised.
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LC50
- Value:
- 3 360 mg/m³ air
- Quality of whole database:
- read across from valid study, no mortality at highest attainable concentration
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Quality of whole database:
- not required since data on two other routes of exposure are available
Additional information
Justification for classification or non-classification
Based on read across from PETMP, PETMA is assumed to be harmful if swallowed (LD50 = 1500 mg/kg bw, Acute Tox 4, H302) and non-toxic if inhaled (no mortality at highest attainable concentration).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.