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Diss Factsheets
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EC number: 219-834-3 | CAS number: 2549-51-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- other: expert assessment
- Adequacy of study:
- key study
- Study period:
- 2017
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The assessment was based on the ready biodegradability of the hydrolysis products of VCA.
- Justification for type of information:
- The assessment was based on the ready biodegradability of the hydrolysis products of VCA.
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- The assessment was based on the ready biodegradability of the hydrolysis products of VCA.
- GLP compliance:
- no
- Inoculum or test system:
- not specified
- Remarks on result:
- other: see 'any other information on results incl. tables'
- Validity criteria fulfilled:
- not applicable
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The registered susbtance degrades upon contact with water and forms hydrolysis products which are further readily biodegradeable, therefore the registered substance can be considered as readily biodegradable.
- Executive summary:
VCA has been found to hydrolyse rapidly (t1/2 < 12 hrs) upon contact with water, to form two main degradation products: Chloroacetic acid (CAS 79-11-8 / EC 201-178-4) and Acetaldehyde (CAS 75-07-0 / EC 200-836-8). It is therefore not scientifically feasible to determine the ready biodegradability of VCA due to the fact it will degrade rapidly in water. In accordance with ECHA’s Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7b, it is advisable to give due consideration to the properties of the degradation products of a rapidly hydrolysable substance. Subsequently, expert judgement has been applied and the ready biodegradability of VCA will be determined from the existing biodegradability data for its degradation products.
Chloroacetic acid and Acetaldehyde are both considered to be readily biodegradable in the aquatic environment. Therefore, since it is known that the registered substance degrades upon contact with water and forms substances which are further readily biodegradable, VCA is to be considered as readily biodegradable for the purpose of endpoint fulfilment. No further testing for this endpoint is required.
Reference
It is not scientifically feasible to determine the biodegradability of VCA, due to the fact that it hydrolyses rapidly in water to form degradation products, Chloroacetic acid and Acetaldehyde. In accordance with ECHA’s Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7b, it is advisable to give due consideration to the properties of the degradation products of a rapidly hydrolysable substance.
Chloroacetic acid and Acetaldehyde are both considered to be readily biodegradable in the aquatic environment. Therefore, since it is known that the registered substance degrades upon contact with water and forms substances which are further readily biodegradable, VCA is to be considered as readily biodegradable for the purpose of endpoint fulfilment. No further testing for this endpoint is required.
Description of key information
VCA has been found to hydrolyse rapidly (t1/2 < 12 hrs) upon contact with water, to form two main degradation products: Chloroacetic acid (CAS 79-11-8 / EC 201-178-4) and Acetaldehyde (CAS 75-07-0 / EC 200-836-8). It is therefore not scientifically feasible to determine the ready biodegradability of VCA due to the fact it will degrade rapidly in water. In accordance with ECHA’s Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7b, it is advisable to give due consideration to the properties of the degradation products of a rapidly hydrolysable substance. Subsequently, expert judgement has been applied and the ready biodegradability of VCA will be determined from the existing biodegradability data for its degradation products.
Chloroacetic acid and Acetaldehyde are both considered to be readily biodegradable in the aquatic environment. Therefore, since it is known that the registered substance degrades upon contact with water and forms substances which are further readily biodegradable, VCA is to be considered as readily biodegradable for the purpose of endpoint fulfilment. No further testing for this endpoint is required.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.