Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 824-801-7 | CAS number: 1093628-27-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of Witconate P-1460 to Daphnia magna (water flea) was tested under static conditions for 48 hours in accordance with OECD 202 and EEC C.2 guidelines for testing chemicals, and ECETOC, Monograph 26 (1996). The test was performed in compliance with Good Laboratory Practice (GLP).
Witconate P-1460 is miscible in water. A preliminary test showed that Witconate P-1460 had a 100% toxicity effect at a test concentration 10 mg/L and an observed NOEC of 1 mg/L having slightly sub lethal effects. Therefore a toxicity test was performed exposing D. magna to a series of test concentrations respectively 0.5, 1.1, 2.3, 4.9 and 10.2 mg/L of test substance.
The results of the definitive test show that the test substance had effect on the mobility of D. magna.
The NOEC and the LOEC (0-48h) of Witconate P-1460 are 2.3 mg/L and 4.9 mg/L respectively. EC50 and EC100 values of respectively 3.6 mg/L (3.3 - 4.0, 95% confidence limits) and 10.2 mg/L were determined. No further sub-lethal effects were observed in the test concentrations where no immobility was observed. The results of the chemical analyses show that the average observed test substance concentrations during the test differs less than 20% from the nominal test concentrations. The results are therefore presented based on their nominal test concentrations.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 3.6 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
