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EC number: 812-963-1 | CAS number: 178436-06-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-04-21 to 2017-10-26
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Version / remarks:
- 27. July 1995
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- GLP compliance:
- no
- Type of method:
- other: DSC + DTG + detection of decomposition by NMR
Test material
- Reference substance name:
- Ceramide IIIB
- IUPAC Name:
- Ceramide IIIB
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
Boiling point
- Key result
- Atm. press.:
- 1 010 hPa
- Decomposition:
- yes
- Decomp. temp.:
- > 275 °C
Any other information on results incl. tables
Capillary method
The melting point / range was determined using a using a melting point system (MP80, Mettler Toledo) according DIN EN ISO 3143 (previous version: DIN 53736). Two runs were done. The onset-temperature is 101 °C. The clear point was reached at 104 °C.
The thermic behaviour ofCeramide III bwas tested with a boiling point capillary from room temperature up to 300 °C with a heating rate of 10 °C/min.
Bubbles rose from approx. 250°C to 275 °C. Finally, after cooling, the content of the tube is colored and brownish residues are obvious at the wall of the tube.
DSC / TGA
As preliminary tests first TGA and DSC runs were performed.
As the substance was obviously modified within the first heating period to 250 °C, the DSC main test was focused on the melting behavior
In the TGA test, a sample of the test item was heated from 30 °C to 675 °C in an inert gas atmosphere (N2). A first drop was detected beginning at 225.0 °C (onset) attended by a weight loss of about 10 %. The main drop was detected beginning at 325.4 °C (onset). Up to 400.2 °C a total weight loss of 99.9 % was recorded.
The recorded main weight loss above 325.4 °C (estimated onset on TGA) may indicate a beginning evaporation (boiling). However, based on the visual inspection and the results of the DSC preliminary test (up to 250°C) where the test item showed a significant change of the melting behaviour (change of the melting point from 102.2 °C to 30.6 °C (peak top)) a product decomposition is more likely.
In order to provide evidence for this assumption, a degradation test was performed during which an aliquot of the sample was heated to 275 °C for 15 minutes. The remaining residue (94.6 % of the original material) war characterised by NMR spectroscopy. The NMR analysis confirms the decomposition of the product. Less than 20 % of the original Ceramide III b material were detected after heating.
Consequently, Ceramide III b does not provide a boiling point until disintegration at about 275 °C.Applicant's summary and conclusion
- Conclusions:
- Ceramide IIIb does not provide a boiling point until disintegration at about 275 °C at 1010 hPa.
- Executive summary:
The heating behaviour of Ceramide IIIb was tested according to OECD103 with visual detection, DTA, DTG and a NMR method. The substance has no melting point but disintegrates (decomposes) above 275 °C (1010 hPa).
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