Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
Die sedative und hypnotische Wirkung des 1-Äthinyl-cyclohexyl-allophanat-(1)
Author:
Keil, Werner; Muschaweck, Roman; Rademacher, Erika
Year:
1954
Bibliographic source:
Arzneimittel-Forschung, Vol.4, pp. 477-9

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
not further specified
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-methylpent-1-en-3-ol
EC Number:
213-044-2
EC Name:
3-methylpent-1-en-3-ol
Cas Number:
918-85-4
Molecular formula:
C6H12O
IUPAC Name:
3-methylpent-1-en-3-ol
Details on test material:
- Name of test material (as cited in study report): 3-methyl-1-Penten-3-ol

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
olive oil
No. of animals per sex per dose:
50 animals total
Control animals:
not specified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 152 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
Category 4 based on GHS criteria