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EC number: 228-762-1 | CAS number: 6358-09-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
2-amino-6-chloro-4-nitrophenol is not readily biodegradable in the manometric respirometry test.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
A ready biodegradation test, following the OECD 301F guideline (Manometric Respirometry Test) and GLP , was conducted on the2-amino-6-chloro-4-nitrophenol.
The substance was tested at 100 mg /L (or 68 mg O2/L on the basis of theoretical oxygen demand (ThOD)). The inoculum was activated sludge collected from the aeration tank of the facility's sewage treatment plant, receiving predominantly domestic sewage. Test treatments and blank were run in duplicate while for toxicity and reference control were run singly.
The test material did not meet the criteria for ready biodegradation. Oxygen consumption, and thus the derived BOD, showed minimal or no degradation of the substance. Measured values from the flask acting as the toxicity control (test and reference material combined) indicated that the test material was not inhibitory to the activated sludge.
Values obtained with the positive control reference substance, sodium benzoate, showed that more than 60% of the ThOD was reached within 14 days, thus demonstrating the validity of the test system. (% degradation on Day 2 = 38.9%, Day 6 = 62.9% and Day 28 = 68.9%).
2 -amino-6 -chloro-4 -nitrophenolis not readily biodegradable in the manometric respirometry test.
This ready biodegradation test is classified as acceptable, and satisfies the guideline requirements for the OECD 301F.
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