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EC number: 435-790-1 | CAS number: 297730-93-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Henry's Law constant
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
The Henry's Law constant of HFE-7500 was determined by the ratio of measured gas-phase concentration over aqueous-phase concentration.
Duplicate test vessels at three headspace:water ratios (70%, 50% and 30%) were incubated at ambient temperature (~23°C) for 4, 5, 6, 7 and 8 days, corresponding to time point 1, 2, 3, 4 and 5. After incubation, duplicate aliquot of the headspace and water phase were removed from each test system vial and transferred to separate vials for analysis. The measured gas phase and water phase concentrations from each aliquots were averaged and used to calculate Henry's Law constant for HFE-7500 for each test vessel. The overall average HLC for HFE-7500 is 19100 (%RSD = 21, n=22). The dimensionless HLC can be converted to 4.7E+07 Pa·m³/mol or 464 atm·m³/mole. This study was conducted under GLP compliance with accepted method. However, there were several samples that had high %RPD. Therefore, it is considered reliable with restrictions and considered as a key study.
Two HLC values were reported based on measured vapor pressure over water solubility. These values are no longer considered.
The photodegradation products of CAS# 297730-93-9, HF, TFA, and PFBA, are highly water soluble and deprotonate readily at environmental pH. They are not expected to be volatile in aquatic systems.
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