Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Effects on fertility

Effect on fertility: via oral route
Dose descriptor:
NOAEL
300 mg/kg bw/day
Additional information

Reproductive and developmental toxicity has been evaluated in an OECD screening study in which animals were treated at dose levels of 0, 20, 100 or 300 mg/kg..

No effects were apparent on reproductive function at any dose level.

Effects on developmental toxicity

Effect on developmental toxicity: via oral route
Dose descriptor:
NOAEL
20 mg/kg bw/day
Additional information

Female rats were administered the substance at doses of 0, 20, 100 or 300 mg/kg/day as part of an OECD screening study for reproductive toxicity.

The only effects of treatment apparent was a reduced body weight gain in pups from the 100 and 300 mg/kg/day treatment groups.

 

Justification for classification or non-classification

No classification for developmental or reproductive toxicity is indicated.

Additional information