Registration Dossier
Registration Dossier
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EC number: 229-052-4 | CAS number: 6408-29-3
Endpoint summary
Administrative data
Description of key information
Skin sensitizer
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
According to the CLP Regulation (EC 1272/2008), 3.4 Respiratory or skin sensitisation section, skin sensitizer means a substance that will lead to an allergic response following skin contact.
A stimulation index of 3 or more is considered a positive response in the Local Lymph Node Assay.Based on the Local Lymph Node Assay test results, a substance in classified as:
- skin sensitiser sub-category 1A, if the EC3 values resulted to be equal/lower than 2 %
- skin sensitiser sub-category 1B, if the EC3 values resulted to be greater than 2 %
Based on the available information, the substance can be considered as a skin sensitizer and it is classified as skin sensitizer sub-category 1B (H317), according to the CLP Regulation (EC 1272/2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
