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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction

Data source

Reference
Reference Type:
other: (Q)SAR
Title:
Estimation Programs Interface Suite™ for Microsoft® Windows, v 4.11 (EPIWEB 4.11)
Author:
United States Environmental Protection Agency, Washington, DC, USA.
Year:
2012
Bibliographic source:
ECOSAR (v1.11)

Materials and methods

Test guideline
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR

Test material

Constituent 1
Chemical structure
Reference substance name:
4-piperidinecarboxylic acid
EC Number:
207-872-3
EC Name:
4-piperidinecarboxylic acid
Cas Number:
498-94-2
Molecular formula:
C6H11NO2
IUPAC Name:
piperidine-4-carboxylic acid
Test material form:
solid

Test organisms

Test organisms (species):
other aquatic crustacea: Daphnid

Study design

Test type:
other: (Q)SAR
Water media type:
freshwater

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
34 178.531 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Remarks:
Aliphatic Amines : Maximum LogKow: 5.0 (Daphnid LC50)
Conclusions:
Estimated LC50 (48 h) :34000 mg/L
Intermediate substance is not estimated to be toxic to aquatic invertebrates (acute toxicity).