Registration Dossier
Registration Dossier
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EC number: 223-892-5 | CAS number: 4111-08-4
Guidance on Safe Use
Guidance on Safe Use
Administrative data
First-aid measures
Inhalation: Remove exposed person to fresh air. If not breathing ensure airway is clear and commence cardiopulmonary resuscitation (CPR). Avoid mouth to mouth contact and use eg. mouth to mask ventilation with one way valve, sacs for artificial lung ventilation, etc. to exhaust victim’s exhaled air away from rescuer. Commence administration of oxygen as soon as possible. Administration of oxygen should be maintained until transfer to the care of a paramedic or doctor. Obtain medical help immediately!
Skin contact: Immediately remove contaminated clothing. Wash contaminated skin with large quantities of (preferably lukewarm) water. If poisoning symptoms appear, follow the above instructions for inhalation exposure. Obtain medical help immediately!
Eye contact: Immediately flush eyes with large quantities of water for 10-15 minutes. While flushing, keep eyelids open even by using force. Obtain medical help immediately!
Ingestion: Obtain medical help immediately! Ingestion of even small amounts is likely to be fatal unless treated rapidly.
Protect yourself and any casualty from further exposure during providing first aid (can be affected also the protective clothing). Wear specified PPE until test confirms no further risk from exposure.
Skin contact: Immediately remove contaminated clothing. Wash contaminated skin with large quantities of (preferably lukewarm) water. If poisoning symptoms appear, follow the above instructions for inhalation exposure. Obtain medical help immediately!
Eye contact: Immediately flush eyes with large quantities of water for 10-15 minutes. While flushing, keep eyelids open even by using force. Obtain medical help immediately!
Ingestion: Obtain medical help immediately! Ingestion of even small amounts is likely to be fatal unless treated rapidly.
Protect yourself and any casualty from further exposure during providing first aid (can be affected also the protective clothing). Wear specified PPE until test confirms no further risk from exposure.
Fire-fighting measures
Suitable extinguishing media are following: fragmented water stream, powder A, B, C, D, CO2, alcohol-resistant foam. Fire- fighting measures are necessary to adapt according to conditions around.
Unsuitable extinguishing media are following: alkali substances since they accelerate the decomposition of product to HCN and butanone.
Use protective chemical suit and self-contained breathing apparatus.
Unsuitable extinguishing media are following: alkali substances since they accelerate the decomposition of product to HCN and butanone.
Use protective chemical suit and self-contained breathing apparatus.
Accidental release measures
In case of accident it is necessary to put on gas mask with type B2 filter (or its equivalent, e.g. combined filter A2B2E2K2P3D) or a self-contained breathing apparatus and protective chemical suit depending on HCN concentration. Indicate contaminated area and do not allow unauthorised personnel to enter.
Prevent further leakage. Avoid penetration to soil, water, sewerage. If the substance penetrates into river or water reservoir, inform the users, stop operation and using the water.
If possible, pump spilled MEKH into a safe container. Vapor, gas shall be condensed using mist. Prevent fire and sparks. Puddles covered with a suitable absorbent material (sorbent, sand, sawdust) and collect into a suitable container marked for further processing or disposal in accordance with local legislation. Spray the contaminated area with diluted sodium hydroxide and subsequently with diluted solution of sodium hypochlorite. In case MEKH penetrated into soil, it is necessary to remove all the contaminated soil and decontaminate it in designed place.
Prevent further leakage. Avoid penetration to soil, water, sewerage. If the substance penetrates into river or water reservoir, inform the users, stop operation and using the water.
If possible, pump spilled MEKH into a safe container. Vapor, gas shall be condensed using mist. Prevent fire and sparks. Puddles covered with a suitable absorbent material (sorbent, sand, sawdust) and collect into a suitable container marked for further processing or disposal in accordance with local legislation. Spray the contaminated area with diluted sodium hydroxide and subsequently with diluted solution of sodium hypochlorite. In case MEKH penetrated into soil, it is necessary to remove all the contaminated soil and decontaminate it in designed place.
Handling and storage
Exhaust ventilation must be provided. When handling the product it is forbidden to eat, drink and smoke until washing properly with soap and hot water. When handling and storing it is necessary to observe safety measures for handling corrosives.
To be stored separately in original sealed packaging units in dry, cool locked storerooms. The storage area must be free of acids and alkali reacting substances, as they carry the risk of releasing highly toxic hydrogen cyanide.
To be stored separately in original sealed packaging units in dry, cool locked storerooms. The storage area must be free of acids and alkali reacting substances, as they carry the risk of releasing highly toxic hydrogen cyanide.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 3276
Shipping information
- Proper shipping name and description:
- NITRILES, TOXIC, LIQUID, N.O.S.
- Chemical name:
- 2-hydroxy-2-methylbutyronitrile
- Language:
- English
- Labels:
- 6.1
Special provisions / remarks
- Remarks:
- Use label for environmentally hazardous substance.
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 3276
Shipping information
- Proper shipping name and description:
- NITRILES, TOXIC, LIQUID, N.O.S.
- Chemical name:
- 2-hydroxy-2-methylbutyronitrile
- Language:
- English
- Labels:
- 6.1
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 3276
Shipping information
- Proper shipping name and description:
- NITRILES, TOXIC, LIQUID, N.O.S.
- Chemical name:
- 2-hydroxy-2-methylbutyronitrile
- Labels:
- 6.1
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 3276
Shipping information
- Proper shipping name and description:
- NITRILES, TOXIC, LIQUID, N.O.S.
- Chemical name:
- 2-hydroxy-2-methylbutyronitrile
- Labels:
- 6.1
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
1. Technical protection measures: Strictly controled conditions
2. Organisational protection measures: It must be ensured the action of 2 workers (so called the buddy system).
3. Hand protection: Gloves- material PVC, thickness min 0.35 mm, penetration time > 30 min
4. Feet protection: Boots
5. Body protection: PVC-coated protective clothing
6. Eye protection: Face mask with antigas filter type B2 or its equivalent (e.g. combined filter A2B2E2K2P3D), self-contained breathing apparatus and/or eye protection.
7. Respiratory protection: Face mask with antigas filter type B2 or its equivalent (e.g. combined filter A2B2E2K2P3D), self-contained breathing apparatus
2. Organisational protection measures: It must be ensured the action of 2 workers (so called the buddy system).
3. Hand protection: Gloves- material PVC, thickness min 0.35 mm, penetration time > 30 min
4. Feet protection: Boots
5. Body protection: PVC-coated protective clothing
6. Eye protection: Face mask with antigas filter type B2 or its equivalent (e.g. combined filter A2B2E2K2P3D), self-contained breathing apparatus and/or eye protection.
7. Respiratory protection: Face mask with antigas filter type B2 or its equivalent (e.g. combined filter A2B2E2K2P3D), self-contained breathing apparatus
Stability and reactivity
MEKH is stable under normal conditions.
Stable in acidic environment. In alcalic environment decomposes into butanon and hydrogen cyanide.
Possibilities of hazardous reactions are not known.
Avoid to direct sunlight, heat and air humidity.
Incompatible materials are following: Strong acids, strong alkalis, oxidising agents, reducing agents, water.
During decomposition can be formed hydrogen cyanide (HCN) and butanone.
Stable in acidic environment. In alcalic environment decomposes into butanon and hydrogen cyanide.
Possibilities of hazardous reactions are not known.
Avoid to direct sunlight, heat and air humidity.
Incompatible materials are following: Strong acids, strong alkalis, oxidising agents, reducing agents, water.
During decomposition can be formed hydrogen cyanide (HCN) and butanone.
Disposal considerations
Dispose of waste and properly empty containers in accordance with applicable waste legislation and other laws and regulations issued to protect the environment. The spilled product clean up according to 6.3. Then hand over to the authorized person to dispose of hazardous waste. The recommended use is use of the material, then energy recovery. Additional information may be provided by the manufacturer.
Recommended waste classification according to the manufacturer according to Decree no. 381/2001 Coll. as amended :
160 305 * - organic waste containing dangerous substances
150110 * - packaging contaminated by hazardous substances
Do not let the product enter sewerage.
Recommended waste classification according to the manufacturer according to Decree no. 381/2001 Coll. as amended :
160 305 * - organic waste containing dangerous substances
150110 * - packaging contaminated by hazardous substances
Do not let the product enter sewerage.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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