3-{3-[(3,5,5-trimethylhexanoyl)oxy]-2,2-bis({[(3,5,5-trimethylhexanoyl)oxy]methyl})propoxy}-2,2-bis({[(3,5,5-trimethylhexanoyl)oxy]methyl})propyl 3,5,5-trimethylhexanoate

Surface tension

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

surface tension

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Reference 2

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

2013-04-10 to 2013-06-20

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: GLP Guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

GLP compliance:

yes (incl. QA statement)

Type of method:

ring method

Surface tension:

72.9 mN/m

Temp.:

21.8 °C

Conc.:

90 vol%

Remarks on result:

other: Not surface active

Surface tension (corrected): reading x calibration factor

Sample A (corrected): 73.1 mN/m x 0.996 = 72.8 mN/m

Sample B (corrected): 73.4 mN/m x 0.996 = 73.1 mN/m

Mean: 72.9 mN/m

Temperature: 21.8 ± 0.5 °C

Solution pH: Sample 1 = 5.6

Sample 2 = 5.6

After the equilibration period, each sample was noted to contain excess, undissolved test item at the surface of the solution; whereas, after centrifugation, each sample (supernatant) was noted to be a clear, colorless solution free from excess, undissolved test item.

A platinum ring with a reduced circumference of 4 cm was used, whereas the guidelines specify 6 cm. Once calibrated, the balance and ring assembly used in this test give a direct reading for surface tension that is within the required accuracy (± 0.5 mN/m). This procedure with respect to the reduced ring dimensions has been considered not to have affected the integrity of the test.

As each (corrected) surface tension value was within 0.5 mN/m of the mean (corrected) value, the mean (corrected) value was considered to be acceptable as the endpoint of the test.

According to criteria mentioned in Method A6, substances showing a surface tension lower than 60 mN/m under the conditions of this method should be regarded as being surface active.

Conclusions:

The surface tension of a 90 % saturated solution in water has been determined to be 72.9 ± 0.5 mN/m at 21.8 ± 0.5 °C. The test item was considered to be not surface-active.

Executive summary:

Guideline

Method A5 Surface Tension of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 115 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Method

Ring method

Result

The surface tension of a 90 % saturated solution in water has been determined to be 72.9 ± 0.5 mN/m at 21.8 ± 0.5 °C.

Conclusion

The test item was considered to be not surface-active.

Reference 3

Endpoint:

surface tension

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

supporting study

Justification for type of information:

To register EC453-460-3 under REACH program, a read-across approach for fulfillment of the endpoints has been adopted. EC453-460-3 is an aliphatic ester and fits the description of polyol esters category in HPV program (High Production Volume, US-EPA). The distinguishing feature of polyol esters category is that the fatty acids were linked to one or more of the multiple hydroxyl groups present in the polyol (alcohol portion of ester). The focus of this correspondence is to support read across to EC613-848-7 (target) which provided key studies to determine hazard profile of EC453-460-3 (target), published information on other structurally analogous polyol esters were served as supporting evidence.

Reason / purpose for cross-reference:

read-across source

Surface tension:

72.9 mN/m

Temp.:

21.8 °C

Conc.:

90 vol%

Remarks on result:

other: Not surface active

Surface tension (corrected): reading x calibration factor

Sample A (corrected): 73.1 mN/m x 0.996 = 72.8 mN/m

Sample B (corrected): 73.4 mN/m x 0.996 = 73.1 mN/m

Mean: 72.9 mN/m

Temperature: 21.8 ± 0.5 °C

Solution pH: Sample 1 = 5.6

Sample 2 = 5.6

After the equilibration period, each sample was noted to contain excess, undissolved test item at the surface of the solution; whereas, after centrifugation, each sample (supernatant) was noted to be a clear, colorless solution free from excess, undissolved test item.

A platinum ring with a reduced circumference of 4 cm was used, whereas the guidelines specify 6 cm. Once calibrated, the balance and ring assembly used in this test give a direct reading for surface tension that is within the required accuracy (± 0.5 mN/m). This procedure with respect to the reduced ring dimensions has been considered not to have affected the integrity of the test.

As each (corrected) surface tension value was within 0.5 mN/m of the mean (corrected) value, the mean (corrected) value was considered to be acceptable as the endpoint of the test.

According to criteria mentioned in Method A6, substances showing a surface tension lower than 60 mN/m under the conditions of this method should be regarded as being surface active.

Conclusions:

The surface tension of a 90 % saturated solution in water has been determined to be 72.9 ± 0.5 mN/m at 21.8 ± 0.5 °C. The test item was considered to be not surface-active.

Executive summary:

Guideline

Method A5 Surface Tension of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 115 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Method

Ring method

Result

The surface tension of a 90 % saturated solution in water has been determined to be 72.9 ± 0.5 mN/m at 21.8 ± 0.5 °C.

Conclusion

The test item was considered to be not surface-active.

Description of key information

Determination of surface tension is not required because water solubility of the test item has been shown to be < 1E-06 g/L of solution at 20.0 ± 0.5 °C.

Additional information

Water solubility of the test item was determined to be < 1E-06 g/L of solution at 20.0 ± 0.5 °C and, in accordance with REACH Annex VII, Column 2, surface tension does not need to be investigated because solubility in water is below 1 mg/L at 20 °C.