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EC number: 810-464-3 | CAS number: 13446-84-9
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Sep. 23,20 15 ~ Dec.24,2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2,2'-[cyclohexane-1,1-diylbis(4,1-phenyleneoxymethylene)]dioxirane
- Cas Number:
- 13446-84-9
- Molecular formula:
- C24H28O4
- IUPAC Name:
- 2,2'-[cyclohexane-1,1-diylbis(4,1-phenyleneoxymethylene)]dioxirane
- Test material form:
- liquid: viscous
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, adapted
- Details on inoculum:
- Industrial sewage treatment plant (4)
Domestic sewage treatment plant (3)
River (4)
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 7.3
- St. dev.:
- 0.7
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- 1) The percentage microbial degradation of the reference item, sodium benzoate, observed by BOD meter was 91.4% after 7 days and 99.9% after 14 days. Thus, these values were within the acceptable range (exceeds than 40% after 7 days and 65% after 14 days) specified by the OECD guidelines and the National Institute of Environmental Research Guidelines.
2) BOD concentration of the inoculurn blank (Bottle 6) after 28 days was 8.4 mg02/L (Table 3). This value was met OECD specifications (less than 60 mg0 2/L).
3) The pH values of test suspension (Bottle 2, 3, 4) after 28 days were 7. 1. These pH value was within the acceptable range (6.0∼8. 5) specified by the OECD guidelines.
4) The percentage microbial degradation of the test item was based on the theoretical oxygen demand (ThOD) which was calculated from the molecular formula and the molecular weight. The percentage microbial degradation of the test item was 7.3 ± 0.7%. This result was not met OECD pass level of biodegradability (60 % ofThOD).
Therefore, the test item (SEZ-250) can be regarded as not readily degradable by microorganisms under the test conditions.
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