Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 230-291-1 | CAS number: 7011-83-8
Endpoint summary
Administrative data
Description of key information
No skin sensitisation in humans was observed for 2 % test substance.
No skin irritation in humans was observed for 2 % test substance.
Additional information
A maximization test in 25 human volunteers was conducted to test the senstising potential of the test substance. The 2 % test substance was applied on the volar forearm or back with an occlusive dressing for 5 alternate-day 48 h periods. The patch sides were pretreated with 2.5 % aqueous sodium lauryl sulfate under occlusion. The challenge side was read immediatly after patch removal and after 24 h. No volunteer showed any reaction on the skin. The test substance was not contact sensitising in humans.
The pre test for this study showed that the 2 % test substance had no skin irritation properties. The occlusive application of the test substance without additional treatment for 48 h on the 25 volunteers caused no skin irritation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
