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EC number: 228-819-0 | CAS number: 6359-98-4
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Remarks:
- Although the values recorded are outside of the applicability domain for the test method, the results can be considered as reliable and representative for the tested substance. The study outcomes are indicative of a high affinity with the water phase, respect than the octanol one.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Version / remarks:
- adopted 27.07.95
- GLP compliance:
- no
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- photometric method
- Type:
- Pow
- Partition coefficient:
- ca. 0.004
- Temp.:
- 20 °C
- pH:
- ca. 6.42
- Remarks on result:
- other: Standard deviation Pow = 0.0003
- Type:
- log Pow
- Partition coefficient:
- ca. -2.459
- Temp.:
- 20 °C
- pH:
- ca. 6.42
- Remarks on result:
- other: Standard deviation log Pow = 0.044
- Conclusions:
- logPow = -2.4586 at 20 °C and at pH of 6.42.
- Executive summary:
Method:
Partition coefficient was determined by means of shake flask method as per recommendations of OECD 107 Guideline. Partition coefficient (P) is defined as the ratio of the equilibrium concentrations of a dissolved substance in a two-phase system consisting in two largely immiscible solvents.
Result:
Study conducted at 20 °C and at pH of 6.42.
The average Pow is 0.0035.
The average logPow is -2.4586.
Reference
Description of key information
logPow: -2.4586 at 20 °C and at pH of 6.42
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -2.459
- at the temperature of:
- 20 °C
Additional information
Partition coefficient was determined by means of shake flask method as per recommendations of OECD 107 Guideline.
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