Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August 1997 - September 1997
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1998
Report date:
1998

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Test type:
acute toxic class method

Test material

Constituent 1
Chemical structure
Reference substance name:
2-bromopropionyl bromide
EC Number:
209-261-7
EC Name:
2-bromopropionyl bromide
Cas Number:
563-76-8
Molecular formula:
C3H4Br2O
IUPAC Name:
2-bromopropanoyl bromide
Test material form:
other: Liquid

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
arachis oil
Doses:
Range finding : 2000, 1000. 500, 200 mg/Kg
Main study : 500, 707, 1000 mg/Kg
No. of animals per sex per dose:
Range finding : 1 male + 1 female
Main study : 5 female
Control animals:
no

Results and discussion

Effect levels
Sex:
female
Dose descriptor:
LD50
Effect level:
>= 707 - <= 1 000 mg/kg bw
Based on:
test mat.
95% CL:
ca. 841

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
841 (707 - 1000) mg/Kg bodyweight