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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From September 28, 2001 to October 05, 2001
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: vapour pressure balance
Temp.:
25 °C
Vapour pressure:
< 0.001 Pa
Temp.:
20 °C
Vapour pressure:
< 0.001 Pa
Temp.:
50 °C
Vapour pressure:
< 0.001 Pa
Transition / decomposition:
yes
Transition temp.:
> 116 °C

The vapour pressure was measured in the temperature range of 29 to 129°C. No signal was observed in the range 29 to 110°C, this means the vapour pressure in this range was below 10E-5 hPa. Above 116°C vapour pressure was measured. The data of the vapour pressure measurement show an unusual scatter varying in the range 1.0x10E-5 to 2.0x10E-5. It has to be concluded, that the measured vapour pressure is caused by the release of volatile decomposition products. This correlates with the decomposition of the test substance observed in the analysis of the DSC (melting point) measurement. Based on these considerations it can be clearly stated that the vapour pressure at 20, 25 and 50°C is far below 10E-5 hPa.

Conclusions:
Under the study conditions, the vapour pressure of the test substance at 25°C was determined to be far below 0.001 Pa.
Executive summary:

A study was conducted to determine the vapour pressure of the test substance according to EU Method A.4 in compliance with GLP.

The determination of vapor pressure was carried out within the temperature range of 29 to 129°C according to the effusion method (vapour pressure balance).

No vapour pressure could be determined in the range of 29 to 110°C, which indicates that the vapour pressure in this range was <10E-5 hPa. Above 116°C, the vapour pressure values displayed an unusual scatter varying from 1.0x10E-5 to 2.0x10E-5 due to the volatile decomposition products of the test substance.

Under the study conditions, the vapour pressure of the test substance at 25°C was determined to be far below 0.001 Pa.

Description of key information

Under the study conditions, the vapour pressure of the test substance at 25°C was determined to be far below 0.001 Pa. 

Key value for chemical safety assessment

Additional information