Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 407-240-9 | CAS number: 159604-94-1 BLUE 10 25 964
Endpoint summary
Administrative data
Description of key information
NOEL (28 days): 1000 mg/kg/day
Key value for chemical safety assessment
- Toxic effect type:
- dose-dependent
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- 1 000 mg/kg bw/day
- Study duration:
- subacute
- Species:
- rat
Repeated dose toxicity: inhalation - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
In this subacute 28-day toxicity study, the test item was administered daily by gavage to SPF-bred Wistar rats. The study comprised of four groups.
FINDINGS:
At 50 mg/kg/day: No treatment-related changes detected.
At 200 mg/kg/day: No treatment-related changes detected.
At 1000 mg/kg/ day: No treatment-related changes detected.
Justification for classification or non-classification
Based on the information available for repeated dose toxicity and according to the CLP Regulation n.1272/2008, table 3.9.1 , the substance is not classified for specific target organ toxicity-repeated exposure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
