Registration Dossier
Registration Dossier
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EC number: 209-057-8 | CAS number: 554-00-7
Long-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well documented publication which meets basic scientific principles.
Data source
Reference
- Reference Type:
- publication
- Title:
- Comparison of the susceptibility of 11 freshwater species to 8 chemical compounds II. (Semi)Chronic toxicity tests.
- Author:
- Slooff W, Canton JH
- Year:
- 1 983
- Bibliographic source:
- Aquat Toxicol 4: 271 - 282
Materials and methods
- Principles of method if other than guideline:
- chronic toxicity to Daphnia magna was tested in a standardized test procedure
- GLP compliance:
- no
Test material
- Reference substance name:
- 2,4-dichloroaniline
- EC Number:
- 209-057-8
- EC Name:
- 2,4-dichloroaniline
- Cas Number:
- 554-00-7
- Molecular formula:
- C6H5Cl2N
- IUPAC Name:
- 2,4-dichloroaniline
- Details on test material:
- - Name of test material (as cited in study report): 2,4-dichloroaniline
- Analytical purity: not given
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Age at the beginning of the test: 1 day
- Source: standardized laboratory culture
- Feeding during test
- Food type: algae (Chlorella)
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Total exposure duration:
- 21 d
Test conditions
- Test temperature:
- 19 +/- 1 °C
- Details on test conditions:
- TEST SYSTEM
- No. of organisms per vessel: 25
- Test volume per group/vessel: 1 l
- No. of vessels per concentration (replicates): 2
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Dutch Standard Water
OTHER TEST CONDITIONS
- Photoperiod: circadic
EFFECT PARAMETERS MEASURED:
- mortality
- reproduction
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 21 d
- Dose descriptor:
- other: NOLC
- Effect conc.:
- 0.032 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.032 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
Any other information on results incl. tables
The result is the most critical and valid NOEC determined for the three trophic levels in aquatic ecosystems. It is used for PNEC derivation.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
