Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 289-530-3 | CAS number: 89899-25-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- None
- Analytical monitoring:
- yes
- Details on sampling:
- No data
- Vehicle:
- not specified
- Details on test solutions:
- M4 medium
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Source: RCC Ltd.
- Age at study initiation (mean and range, SD): Young daphnids, aged less than ‘24’ hours old - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Post exposure observation period:
- None
- Hardness:
- 220 mg/L
- Test temperature:
- 20.7- 20.8 °C
- pH:
- 7.69 - 7.88
- Dissolved oxygen:
- 7.63 – 7.78 mg/L
- Salinity:
- Not available
- Conductivity:
- Not available
- Nominal and measured concentrations:
- 0.30, 0.60, 1.20 2.40, 4.80, 9.60 and 19.20 mg/L
- Details on test conditions:
- TEST SYSTEM
- No. of organisms per vessel: 10 daphnids - Reference substance (positive control):
- yes
- Remarks:
- Potassium Dichromate Pure
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 4.4 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- LOEC
- Effect conc.:
- 1.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Results with reference substance (positive control):
- Based on the test results, the EC50 of Potassium Dichromate Pure in Daphnia magna observed for a period of ‘24’ hour was calculated as 1.72 mg/L with upper confidence limits of 2.12 mg/L and lower confident limits of 1.40 mg/L and regression equation Y = 4.0957 + 3.8604 log (x). At ‘48’ hour, the EC50 was calculated as 1.33 mg/L with upper confidence limits of 1.63 mg/L and lower confidence limits of 1.08 mg/L and regression equation Y = 4.5239 + 3.8769 log (x).
- Reported statistics and error estimates:
- None
- Validity criteria fulfilled:
- yes
- Conclusions:
- The EC50 of FAT 20290/C TE in Daphnia magna observed for a period of 48 hour was calculated as 4.40 mg/L.
- Executive summary:
Acute Immobilization Toxicity Study in Daphnia magna was conducted in accordance with OECD guideline 202 with FAT 20290/C TE. Based on the results of the range finding experiment, main experiment was conducted with a range of concentrations viz., 0.30, 0.60, 1.20, 2.40, 4.80, 9.60 and 19.20 mg/L.
No immobilization was observed in control and daphnids exposed to 0.30 and 0.60 mg/L test concentration throughout the experimental period. At the end of 24-hour observation period, no immobility was observed in daphnids exposed to 1.20, 2.40 and 4.80 mg/L concentration whereas, 7/40 and 14/40 immobility was observed in daphnids exposed to 9.60 and 19.20 mg/L concentrations respectively. Thus, the percent immobilization at the end of 24-hour observation period was recorded to be 0 % in control and daphnids exposed to 0.30, 0.60, 1.20, 2.40 and 4.80 mg/L concentrations whereas, 17.5 % and 35 % was observed in daphnids exposed to 9.60 and 19.20 mg/L concentrations respectively. At the end of 48-hour observation period, 3/40, 7/40 and 14/40 immobile animals were recorded in the daphnids exposed to 1.20, 2.40 and 4.80 mg/L concentration whereas, 39/40, 40/40 cumulative immobility was observed in daphnids exposed to 9.60 and 19.20 mg/L concentration. Thus, the percent cumulative immobilization at the end of 48 hour was recorded to be 0 % in control and daphnids exposed to 0.30, and 0.60 mg/L test concentrations whereas, 7.5 %, 17.5 %, 35 %, and 97.5 % was observed in daphnids exposed to 1.20, 2.40, 4.80 and 9.60 mg/L concentrations and 100 % was observed in daphnids exposed to 19.20 mg/L concentration.
The EC50 of FAT 20290/C TE in Daphnia magna observed for a period of 48 hour was calculated as 4.40 mg/L with upper confidence limits of 6.64 mg/L and lower confidence limits of 2.93 mg/L and regression equation Y = 2.7293+3.5279 log (x).
The no observed effect concentration (NOEC) and the low observed effect concentration (LOEC) for 48 hours was calculated as 0.60 mg/L and 1.20 mg/L, respectively.
Reference
No immobilization was observed in control and daphnids exposed to 0.30 and 0.60 mg/L test concentration throughout the experimental period. At the end of 24 hour, no immobility was observed in daphnids exposed to 1.20, 2.40 and 4.80 mg/L concentration whereas, 7/40 and 14/40 immobility was observed in daphnids exposed to 9.60 and 19.20 mg/L concentrations respectively. Thus, the percent immobilisation at the end of 24 hour was recorded to be 0 % in control and daphnids exposed to 0.30, 0.60, 1.20, 2.40 and 4.80 mg/L concentrations whereas, 17.5 % and 35 % was observed in daphnids exposed to 9.60 and 19.20 mg/L concentrations respectively. At the end of 48 hour, 3/40, 7/40 and 14/40 immobility was recorded in the daphnids exposed to 1.20, 2.40 and 4.80 mg/L concentration whereas, 39/40, 40/40 cumulative immobility was observed in daphnids exposed to 9.60 and 19.20 mg/L concentration. Thus the percent cumulative immobilisation at the end of 48 hour was recorded to be 0% in control and daphnids exposed to 0.30, and 0.60 mg/L test concentrations whereas, 7.5 %, 17.5 %, 35 %, and 97.5 % was observed in daphnids exposed to 1.20, 2.40, 4.80 and 9.60 mg/L concentrations and 100 % was observed in daphnids exposed to 19.20 mg/L concentration.
Based on the test results, the EC50 of FAT 20290/C TE in Daphnia magna observed for a period of 24 hour was calculated as 24.07 mg/L with upper confidence limits of 43.27 mg/L and lower confidence limits of 18.27 mg/L and regression equation Y = 0.8956 +2.9711 log (x).
The EC50 of FAT 20290/C TE in Daphnia magna observed for a period of 48 hour was calculated as 4.40 mg/L with upper confidence limits of 6.64 mg/L and lower confidence limits of 2.93 mg/L and regression equation Y = 2.7293+3.5279 log (x).
The no observed effect concentration (NOEC) and the low observed effect concentration (LOEC) for 24 hours was calculated as 4.80 mg/L and 9.60 mg/L respectively.
The no observed effect concentration (NOEC) and the low observed effect concentration (LOEC) for 48 hours was calculated as 0.60 mg/L and 1.20 mg/L respectively.
Description of key information
The EC50 of FAT 20290/C TE in Daphnia magna observed for a period of 48 hours was calculated as 4.40 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 4.4 mg/L
Additional information
Acute Immobilization Toxicity Study in Daphnia magna was conducted in accordance with OECD guideline 202 with FAT 20290/C TE. Based on the results of the range finding experiment, main experiment was conducted with a range of concentrations viz., 0.30, 0.60, 1.20, 2.40, 4.80, 9.60 and 19.20 mg/L.
No immobilization was observed in control and daphnids exposed to 0.30 and 0.60 mg/L test concentration throughout the experimental period. At the end of 24-hour observation period, no immobility was observed in daphnids exposed to 1.20, 2.40 and 4.80 mg/L concentration whereas, 7/40 and 14/40 immobility was observed in daphnids exposed to 9.60 and 19.20 mg/L concentrations respectively. Thus, the percent immobilization at the end of 24-hour observation period was recorded to be 0 % in control and daphnids exposed to 0.30, 0.60, 1.20, 2.40 and 4.80 mg/L concentrations whereas, 17.5 % and 35 % was observed in daphnids exposed to 9.60 and 19.20 mg/L concentrations respectively. At the end of 48-hour observation period, 3/40, 7/40 and 14/40 immobile animals were recorded in the daphnids exposed to 1.20, 2.40 and 4.80 mg/L concentration whereas, 39/40, 40/40 cumulative immobility was observed in daphnids exposed to 9.60 and 19.20 mg/L concentration. Thus, the percent cumulative immobilization at the end of 48 hour was recorded to be 0 % in control and daphnids exposed to 0.30, and 0.60 mg/L test concentrations whereas, 7.5 %, 17.5 %, 35 %, and 97.5 % was observed in daphnids exposed to 1.20, 2.40, 4.80 and 9.60 mg/L concentrations and 100 % was observed in daphnids exposed to 19.20 mg/L concentration.
The EC50 of FAT 20290/C TE in Daphnia magna observed for a period of 48 hour was calculated as 4.40 mg/L with upper confidence limits of 6.64 mg/L and lower confidence limits of 2.93 mg/L and regression equation Y = 2.7293+3.5279 log (x).
The no observed effect concentration (NOEC) and the low observed effect concentration (LOEC) for 48 hours was calculated as 0.60 mg/L and 1.20 mg/L, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.