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Reaction mass of Cobaltate(1-), bis[6-(amino-κN)-5-[2-[2-(hydroxy-κO)-4-nitrophenyl]diazenyl-κN1]-N-methyl-2-naphthalenesulfonamidato(2-)]-, sodium (1:1) and disodium [6-amino-5-[(2-hydroxy-4-nitrophenyl)azo]-N-methylnaphthalene-2-sulphonamidato(2-)][6-amino-5-[(2-hydroxy-4-nitrophenyl)azo]naphthalene-2-sulphonato(3-)]cobaltate(2-)
EC number: 943-062-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1991
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- not specified
- Principles of method if other than guideline:
- Method A-11
- GLP compliance:
- no
- Specific details on test material used for the study:
- None
- Analytical monitoring:
- yes
- Details on sampling:
- Not available
- Vehicle:
- yes
- Details on test solutions:
- Not available
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- Zebrafish:(Danio rerio)
Replicates: 10 per test concentration
Age: about 4-6 months
Size: about 3 cm
Weight: 0.25-0.35 g
Supplier: West Aquarium GmbH, D-3422 Bad Lauterberg - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Post exposure observation period:
- Not available
- Hardness:
- Not available
- Test temperature:
- ca. 23 °C
- pH:
- 8.0 - 8.1
- Dissolved oxygen:
- 82, 94 and 87 %
- Salinity:
- Not available
- Conductivity:
- Not available
- Nominal and measured concentrations:
- 100, 300 and 1000 mg/l
- Details on test conditions:
- Not available
- Reference substance (positive control):
- not specified
- Duration:
- 48 h
- Dose descriptor:
- LC0
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 449.95 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC100
- Effect conc.:
- 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 305.77 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- At 100 mg/l: all fish were alive after 96 h
At 300 mg/l : 7 fish were alive after 96 h
At 1000 mg/l : all fish died after 48 h - Results with reference substance (positive control):
- Not available
- Reported statistics and error estimates:
- Not available
- Sublethal observations / clinical signs:
Concentration
Survivors
1 h
4 h
24 h
48 h
72 h
96 h
100 mg/l
10
10
10
10
10
10
300 mg/l
10
10
9
9
7
7
1000 mg/l
10
10
1
0
0
0
- Validity criteria fulfilled:
- no
- Conclusions:
- The LC50 of FAT 20036/E in a short term fish toxicity test was found to be 305.77 mg/l after 96h of exposure.
- Executive summary:
A test was carried out in Zebra fish to determine short term toxicity of FAT 20036/E according to method equivalent or similar to OECD Guideline 203 (Fish, Acute Toxicity Test) at concentrations of 100, 300 and 1000 mg/l.
At 100 mg/l: all fish were alive after 96 h
At 300 mg/l : 7 fish were alive after 96 h
At 1000 mg/l : all fish died after 48 h
The following results were found:
LC0 (48h): 100 mg/L
LC50 (48h): 449.95 mg/L
LC100 (48h): 1000 mg/L
LC0 (96h): 100 mg/l
LC50 (96h): 305.77 mg/l
LC100 (96h): 1000 mg/l
The LC50 of FAT 20036/E in a short term fish toxicity test was found to be 305.77 mg/l after 96h of exposure.
Reference
Description of key information
The LC50 for FAT 20036 in the acute fish toxicity test was determined to be 449.95 mg/l at 48 hours exposure time and 305.77 mg/l at 96 hours of exposure time.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 305.77 mg/L
Additional information
A key study was carried out in Zebra fish to determine short term toxicity of FAT 20036/E equivalent or similar to OECD Guideline 203 (Fish, Acute Toxicity Test) at concentrations of 100, 300 and 1000 mg/l.
The LC50 in the acute fish toxicity test was determined to be 449.95 mg/l at 48 hours exposure time and 305.77 mg/l at 96 hours of exposure time.
In several supporting studies, following results were obtained:
TL0 (48 h) – 20, 100 and 30 mg/l
TL50 (48 h) – 45, 586, 103 and 274 mg/l
TL100 (48 h) -100 and 1000 mg/l
TL0 (96 h) – 100 and <30 mg/l
TL50 (96 h) – 382, 42 and 183 mg/l
TL100 (96 h) – 1000 and 300 mg/l
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