Registration Dossier
Registration Dossier
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EC number: 232-102-8 | CAS number: 7786-67-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 5-methyl-2-(1-methylvinyl)cyclohexan-1-ol
- EC Number:
- 232-102-8
- EC Name:
- 5-methyl-2-(1-methylvinyl)cyclohexan-1-ol
- Cas Number:
- 7786-67-6
- Molecular formula:
- C10H18O
- IUPAC Name:
- 5-methyl-2-(prop-1-en-2-yl)cyclohexan-1-ol
- Details on test material:
- name of test material: Isopulegol
Constituent 1
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- From the culture lab
Study design
- Water media type:
- freshwater
- Total exposure duration:
- 72 h
Test conditions
- Test temperature:
- 21 to 24 °C
- pH:
- 8.23
- Nominal and measured concentrations:
- Isopulegol nominal Concentration (mg/L): 100
Isopulegol experimental concentration (mg/L): 95.7 - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- other: ErC50 (Growth inhibition)
- Effect conc.:
- 28.8 mg/L
- Duration:
- 72 h
- Dose descriptor:
- other: ErC10 (Growth inhibition)
- Effect conc.:
- 8.92 mg/L
- Duration:
- 72 h
- Dose descriptor:
- other: EyC50 (Inhibition of Yield)
- Effect conc.:
- 15.6 mg/L
- Duration:
- 72 h
- Dose descriptor:
- other: EyC10 (Inhibition of Yield)
- Effect conc.:
- 11.7 mg/L
- Results with reference substance (positive control):
- ErC50-72h K2Cr2O7 = 1.15 mg/L
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- ErC50-72h (Growth inhibition) = 28.8 mg/L
EyC50-72h (Inhibition of yield) = 15.6 mg/L
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