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EC number: 215-170-3 | CAS number: 1309-42-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Health surveillance data
Administrative data
- Endpoint:
- health surveillance data
- Type of information:
- other: Consortium questionnaire
- Adequacy of study:
- supporting study
Data source
Reference
- Reference Type:
- other: other, consortium questionnaires
- Title:
- Summary of received human health questionnaires from magnesium hydroxide manufacturing sites
- Year:
- 2 010
Materials and methods
- Study type:
- self-reporting of symptoms
- Endpoint addressed:
- other: Human health
- Principles of method if other than guideline:
- Human health questionnaire to Consortium members.
Test material
- Reference substance name:
- Magnesium hydroxide
- EC Number:
- 215-170-3
- EC Name:
- Magnesium hydroxide
- Cas Number:
- 1309-42-8
- Molecular formula:
- H2MgO2
- IUPAC Name:
- magnesium dihydroxide
Constituent 1
Method
- Type of population:
- occupational
- Ethical approval:
- not specified
- Details on study design:
- A human health questionnaire was distributed among eight companies where, overall, 457 workers are exposed to magnesium hydroxide, 182 of those are exposed continuously and 227 are exposed intermittently. These workers were questioned on any adverse effects they may have experienced due to the exposure; these included occupational asthma, allergy or occupational asthma confirmed by medical testing or any other cases of health problems which may have been reported.
Results and discussion
- Results:
- No exposure related health problems including allergy or occupational asthma, were reported. There were also no adverse effects reported from the workers during each operation, even in cases where PPE was not used for some of the procedures in some companies.
Applicant's summary and conclusion
- Conclusions:
- No adverse health effects reported.
- Executive summary:
A human health questionnaire was distributed among eight companies where, overall, 457 workers are exposed to magnesium hydroxide, 182 of those are exposed continuously and 227 are exposed intermittently. These workers were questioned on any adverse effects they may have experienced due to the exposure; these included occupational asthma, allergy or occupational asthma confirmed by medical testing or any other cases of health problems which may have been reported. Among all the workers surveyed, there were no reported cases, from any of the 457 workers in all 8 companies, of health problems or adverse effects experienced through exposure.
During each operation, different forms of personal protective equipment were used in order to protect the worker from any adverse effects related to magnesium hydroxide exposure, these included gloves, goggles, respirator and protective suits. For any operation which involved pouring, lab operations or disposal, PPE was used to protect the workers. For a number of different operations, in different companies, including filling/loading/ emptying/ transferring and weighing and mixing, no PPE is used by workers when carrying out these procedures and no adverse effects were reported after exposure to the Magnesium hydroxide during processing.
In addition, the engineering procedures in each company were examined, for example if they had local and general ventilation and if the workers were separated from the exposure source, and the majority of companies had these engineering procedures in place where applicable to the operation.
In conclusion, according to the human health questionnaires distributed through 8 different companies where 457 total workers are exposed to Magnesium hydroxide on a regular basis, no exposure related health problems including allergy or occupational asthma, were reported. There were also no adverse effects reported from the workers during each operation, even in cases where PPE was not used for some of the procedures in some companies.
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