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EC number: 270-109-8 | CAS number: 68411-20-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Abiotic degradation:
Both, biotic and abiotic degradation studies show that the substance is partially degradable. In the hydrolysis study about 30% of primary degradation was observed yielding aniline as the main hydrolysis product. Similar degradation rates were observed in ready biodegradation tests assuming that aniline is formed hydrolytically in this study which is then biodegraded.
Biotic degradation:
In different tests according to OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test) and to OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test) degradation rates between 24% and 37% were observed. In conclusion butanal, reaction products with aniline is not readily biodegradable. A further test according to OECD Guideline 302 C (Inherent Biodegradability: Modified MITI Test (II)) showed 39% degradataion after 56 days.
According to section 1 of REACH annex XI, the performance of a study for Biodegradation in a water-sediment system and for biodegradation in soil are scientifically unjustified. In biodegradation test in water, biodegradation of about 30 to 40% was noticed. This percentage reflects to the part of butanal, reaction products with aniline hydrolysing rapidly to aniline. The remaining 70% were found stable under test conditions.
Bioaccumulation
Curently no study on the bioaccumulation of the substance in fish is available, and it shall be discussed whether a study is needed and feasible. Technical feasability or non-feasability is considered as follows:
1. UVCB: The substance is UVCB and consists of components which can be characterised as quasi-homologues of aniline and butanal in several molar relations. Eleven clusters of components have been characterised. However, the exact structures are not known, and several isomers of the tentatively assigned structures are possible. Additionally about 10% unidentified components are contained.
2. Instability: A portion of about 30% of the substance hydrolyses quickly at pH7 even at room temperature. At 70°C, the formation of aniline is complete after 31 minutes. One main end-product after hydrolysis and especially under photolytical conditions is formed which is tentatively 3 -ethyl-4 -propyl-quinoline.
3. Complex reactivity: A BCF test even in a flow-through system would require a stock container with the dissolved substance. Reaction of the substance is expected to occur in this container. Due to the complex reaction pattern in water where some components are hydrolysed but others are formed, it is predictable that stable conditions cannot be obtained which are required for a proper calculation of the BCF.
As a conclusion, a bioconcentration test would be technically extremely difficult or not feasable at all.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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